Imidazolium-based ionic liquid surfactants as pseudostationary in combination with a chiral selector in micellar electrokinetic chromatography

Feng, Zijie; Ju, Ling; Tao, Yu; Du, Yingxiang; Sun, Xiaodong

doi:10.1007/s00216-019-01861-8

Cited by 13 publications

(3 citation statements)

References 23 publications

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“…The presence of salts in the separation buffer affects factors such as solute adsorption on capillary walls, ionic strength of the buffer solution, and electroosmotic flow [ 29 ]. In this experiment, a constant composition of MeOH-ACN 60:40 (v/v), 60 mmol/L TFA, and 20 mmol/L SDS was maintained, while investigating the effects of NaAc, Na 2 HPO 4 , NaH 2 PO 4 , and NH 4 Ac.…”

Section: Resultsmentioning

confidence: 99%

Comparison of aqueous and non-aqueous capillary electrophoresis for the determination of four benzalkonium chloride homologues in compound chemical disinfectants

Yao,

Jiang,

Wang

et al. 2024

Heliyon

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Section: Resultsmentioning

confidence: 99%

Comparison of aqueous and non-aqueous capillary electrophoresis for the determination of four benzalkonium chloride homologues in compound chemical disinfectants

Yao,

Jiang,

Wang

et al. 2024

Heliyon

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“…CILs have attracted much attention for several applications, such as chiral solvents, asymmetric synthesis, a, recently, chiral CE for the separation of enantiomers. CILs are commonly used as chiral selectors, chiral ligands, and in the BGE, as listed in Table 2 [114–154]. ACILs such as the ones based on alkylpyridinium, alkyl imidazolium, and tetraalkylammonium are also used in CE separation with combinations of β‐CD derivatives and furnish a favored interaction with enantiomers.…”

Section: Electrophoretic Methods For Enantioseparationmentioning

confidence: 99%

From capillaries to microchips, green electrophoretic features for enantiomeric separations: A decade review (2013–2022)

Aredes,

Lima,

Faillace

et al. 2023

Electrophoresis

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Enantioseparation by the electromigration‐based method is well‐established and widely discussed in the literature. Electrophoretic strategies have been used to baseline resolve complex enantiomeric mixtures, typically using a selector substance into the background electrolyte (BGE) from capillaries to microchips. Along with developing new materials/substances for enantioseparations, it is the concern about the green analytical chemistry (GAC) principles for method development and application. This review article brings a last decade's update on the publications involving enantioseparation by electrophoresis for capillary and microchip systems. It also brings a critical discussion on GAC principles and new green metrics in the context of developing an enantioseparation method. Chemical and green features of native and modified cyclodextrins are discussed. Still, given the employment of greener substances, ionic liquids and deep‐eutectic solvents are highlighted, and some new selectors are proposed. For all the mentioned selectors, green features about their production, application, and disposal are considered. Sample preparation and BGE composition in GAC perspective, as well as greener derivatization possibilities, were also addressed. Therefore, one of the goals of this review is to aid the electrophoretic researchers to look where they have not.

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“…3 [69,[167][168][169][170]. As some ILs resemble surfactants, they can also be employed as PSP in chiral MEKC analysis [160,161,171]. Novel developments include the fabrication of monolithic IL columns and IL silica hybrids, as well as polymeric ILs that resemble molecular micelles [161].…”

Section: Chiral Ionic Liquidsmentioning

confidence: 99%

Past, present, and future developments in enantioselective analysis using capillary electromigration techniques

2020

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Past, present, and future developments in enantioselective analysis using capillary electromigration techniques Enantioseparation of chiral products has become increasingly important in a large diversity of academic and industrial applications. The separation of chiral compounds is inherently challenging and thus requires a suitable analytical technique that can achieve high resolution and sensitivity. In this context, CE has shown remarkable results so far. Chiral CE offers an orthogonal enantioselectivity and is typically considered less costly than chromatographic techniques, since only minute amounts of chiral selectors are needed. Several CE approaches have been developed for chiral analysis, including chiral EKC and chiral CEC. Enantioseparations by EKC benefit from the wide variety of possible pseudostationary phases that can be employed. Chiral CEC, on the other hand, combines chromatographic separation principles with the bulk fluid movement of CE, benefitting from reduced band broadening as compared to pressure-driven systems. Although UV detection is conventionally used for these approaches, MS can also be considered. CE-MS represents a promising alternative due to the increased sensitivity and selectivity, enabling the chiral analysis of complex samples. The potential contamination of the MS ion source in EKC-MS can be overcome using partial-filling and counter-migration techniques. However, chiral analysis using monolithic and open-tubular CEC-MS awaits additional method validation and a dedicated commercial interface. Further efforts in chiral CE are expected toward the improvement of existing techniques, the development of novel pseudostationary phases, and establishing the use of chiral ionic liquids, molecular imprinted polymers, and metalorganic frameworks. These developments will certainly foster the adoption of CE(-MS) as a well-established technique in routine chiral analysis.

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Imidazolium-based ionic liquid surfactants as pseudostationary in combination with a chiral selector in micellar electrokinetic chromatography

Cited by 13 publications

References 23 publications

Comparison of aqueous and non-aqueous capillary electrophoresis for the determination of four benzalkonium chloride homologues in compound chemical disinfectants

Comparison of aqueous and non-aqueous capillary electrophoresis for the determination of four benzalkonium chloride homologues in compound chemical disinfectants

From capillaries to microchips, green electrophoretic features for enantiomeric separations: A decade review (2013–2022)

Past, present, and future developments in enantioselective analysis using capillary electromigration techniques

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