Imitation of optical coherence tomography images by wave Monte Carlo-based approach implemented with the Leontovich–Fock equation

Bulygin, A. D.; Vrazhnov, Denis A.; Sim, Elena S.; Meglinski, Igor; Kistenev, Yury V.

doi:10.1117/1.oe.59.6.061626

Cited by 7 publications

(11 citation statements)

References 51 publications

(62 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…where n n n   defines random variations of the refractive index of the medium, with a separated regular and fluctuation part, respectively. The random Gaussian field of fluctuations of the medium is constructed following the model in [5,15], where for the correlation function of the field n  following relation is held…”

Section: Mathematical Model Of the Propagation Problemmentioning

confidence: 99%

“…The defined set of these parameters determines the type of biological tissue [15]. These parameters can be correlated with the parameters of the indicatrix of the medium [5] used in the corpuscular Monte Carlo method for modeling the propagation of radiation in biological tissue.…”

Section: Mathematical Model Of the Propagation Problemmentioning

confidence: 99%

“…To solve equation ( 4), the method of splitting in physical parameters was used, similar to [5]. At the diffraction propagation step, equation ( 2) is solved, which has the following form…”

Section: Numerical Modelingmentioning

confidence: 99%

“…Nowadays the imaging of biological tissues utilizing optical coherence tomography (OCT) is widely in use [1][2][3][4][5]. The variation of the depth of visualization and spatial resolution of the technique can be achieved utilizing focusing lenses.…”

Section: Introductionmentioning

confidence: 99%

“…In this case, it is necessary to take into account the transverse structure of the probing optical radiation. Typically, the bounded optical beams with a Gaussian transverse profile are used [1][2][3]5].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Imitation of ultra-sharp light focusing within turbid tissue-like scattering medium by using time-independent Helmholtz equation and method Monte Carlo

Buligin

Kistenev

Meglinski

et al. 2020

Fourth International Conference on Terahertz and Microwave Radiation: Generation, Detection, and Applications

Self Cite

View full text Add to dashboard Cite

Based on time-independent Helmholtz equation and its solution in frame of inhomogeneous approximation a hybrid computational method for imitation of propagation of bounded laser beam focused into biological tissue is introduced. The biological tissue is simulated as a semi-infinite randomly inhomogeneous medium. The developed approach is intended to model laser beams in the super-sharp focusing mode. The results of modeling of laser light focusing into the turbid tissue-like scattering medium with lenses of various shapes are presented.

show abstract

Section: Mathematical Model Of the Propagation Problemmentioning

confidence: 99%

Section: Mathematical Model Of the Propagation Problemmentioning

confidence: 99%

“…To solve equation ( 4), the method of splitting in physical parameters was used, similar to [5]. At the diffraction propagation step, equation ( 2) is solved, which has the following form…”

Section: Numerical Modelingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Imitation of ultra-sharp light focusing within turbid tissue-like scattering medium by using time-independent Helmholtz equation and method Monte Carlo

Buligin

Kistenev

Meglinski

et al. 2020

Fourth International Conference on Terahertz and Microwave Radiation: Generation, Detection, and Applications

Self Cite

View full text Add to dashboard Cite

show abstract

Light distribution in fat cell layers at physiological temperatures

I.Yu.¹,

Dyachenko²,

Shalin³

et al. 2023

Sci Rep

View full text Add to dashboard Cite

Adipose tissue (AT) optical properties for physiological temperatures and in vivo conditions are still insufficiently studied. The AT is composed mainly of packed cells close to spherical shape. It is a possible reason that AT demonstrates a very complicated spatial structure of reflected or transmitted light. It was shown with a cellular tissue phantom, is split into a fan of narrow tracks, originating from the insertion point and representing filament-like light distribution. The development of suitable approaches for describing light propagation in a AT is urgently needed. A mathematical model of the propagation of light through the layers of fat cells is proposed. It has been shown that the sharp local focusing of optical radiation (light localized near the shadow surface of the cells) and its cleavage by coupling whispering gallery modes depends on the optical thickness of the cell layer. The optical coherence tomography numerical simulation and experimental studies results demonstrate the importance of sharp local focusing in AT for understanding its optical properties for physiological conditions and at AT heating.

show abstract

Computationally efficient model of OCT scan formation by focused beams and its usage to demonstrate a novel principle of OCT-angiography

Matveyev¹,

Matveev²,

Moiseev³

et al. 2020

Laser Phys. Lett.

View full text Add to dashboard Cite

A computationally highly efficient full-wave model of OCT-scan formation by focused beams in spectral-domain optical coherence tomography (OCT) is presented. Similarly to some previous models, it is based on summation of fields scattered by discrete sub-resolution scatterers and enables accounting for axial and lateral inhomogeneity of the illuminating Gaussian beam. The main feature ensuring high computational efficiency of the described model is that instead of numerical integration of the scattered signal over the receiving aperture we apply analytical description of both the illuminating-beam focusing and collection of the scattered signals over the receiving aperture. Elimination of numerical integration over the receiving aperture has increased the computation speed by a factor of ~3 10. This is of key importance for practical feasibility of simulations of 3D OCT data volumes for large amounts (~7 5 10 10 ) of scatterers corresponding to realistic densities of cells in biological tissues. We demonstrate the model possibilities by simulating digital refocusing of strongly focused OCT beams in the presence moving scatterers. A novel principle of contrast-agent-free visualization of scatterer flows with velocities typical of blood microcirculation is demonstrated.

show abstract

Imitation of optical coherence tomography images by wave Monte Carlo-based approach implemented with the Leontovich–Fock equation

Cited by 7 publications

References 51 publications

Imitation of ultra-sharp light focusing within turbid tissue-like scattering medium by using time-independent Helmholtz equation and method Monte Carlo

Imitation of ultra-sharp light focusing within turbid tissue-like scattering medium by using time-independent Helmholtz equation and method Monte Carlo

Light distribution in fat cell layers at physiological temperatures

Computationally efficient model of OCT scan formation by focused beams and its usage to demonstrate a novel principle of OCT-angiography

Contact Info

Product

Resources

About