Human altruistic responding (called give responding), which delivered a reinforcer to someone other than the responder, was compared to responding where the responder was the recipient of the reinforcer (called earn responding). The same type of response (button pressing), the same reinforcer (a point representing a penny), and the same reinforcer contingency (a 40-response fixed-ratio schedule) were used for both give and earn responding. Since points representing pennies were used to reinforce give and earn responding, responding for points not worth money was also assessed. Give, earn, and point responding were arranged as concurrent incompatible operants. Lowest rates were obtained for point responding. Compared to earn responding, give responding occurred at lower rates, was more susceptible to cessation when point responding was possible, extinguished more rapidly in the absence of money, and produced less responding during reconditioning compared to conditioning when reconditioning followed a period of nonreinforcement. Give responding was less when it reduced the giver's opportunity to earn. Finally, histories of getting reinforcement from others were shown to determine give responding.