Immediate parent-infant skin-to-skin study (IPISTOSS): study protocol of a randomised controlled trial on very preterm infants cared for in skin-to-skin contact immediately after birth and potential physiological, epigenetic, psychological and neurodevelopmental consequences

Linnér, Agnes; Westrup, Björn; Lode-Kolz, Karoline; Klemming, Stina; Lilliesköld, Siri; Pike, Hanne Markhus; Morgan, Barak; Bergman, Nils; Rettedal, Siren; Jonas, Wibke

doi:10.1136/bmjopen-2020-038938

Cited by 30 publications

(31 citation statements)

References 61 publications

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“…It rather had a negative impact on the mother-child-bond. 43 Therefore, this drastic sanction is questionable. In our analysis, swabs from vaginal secretion, cord blood and placenta were all negative.…”

Section: Discussionmentioning

confidence: 99%

Characterization of neonates born to mothers with SARS-CoV-2 infection: Review and meta-analysis

Neef

Buxmann

Rabenau

et al. 2021

Pediatrics & Neonatology

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Objective Characterization of neonates born to mothers with SARS-CoV-2 infection has been partially carried out. There has been no systematic review providing a holistic neonatal presentation including possible vertical transmission. Study design A systematic literature search was performed using PubMed, Google Scholar and Web of Science up to June, 6 2020. Studies on neonates born to mothers with SARS-CoV-2 infection were included. A binary random effect model was used for prevalence and 95% confidence interval. Results 32 studies involving 261 neonates were included in meta-analysis. Most neonates born to infected mothers did not show any clinical abnormalities (80.4%). Clinical features were dyspnea in 11 (42.3%) and fever in 9 newborns (19.1%). Of 261 neonates, 120 neonates were tested for infection, of whom 12 (10.0%) tested positive. Swabs from placenta, cord blood and vaginal secretion were negative. Conclusions Neonates are mostly non affected by the mother`s SARS-CoV-2 infection. The risk of vertical transmission is low.

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Section: Discussionmentioning

confidence: 99%

Characterization of neonates born to mothers with SARS-CoV-2 infection: Review and meta-analysis

Neef

Buxmann

Rabenau

et al. 2021

Pediatrics & Neonatology

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“…Effective communication and assiduous monitoring are vital throughout. Over the next few years, further evidence regarding the safety and benefits of the DRC will emerge from prospective studies presently underway in centres that have already adopted the practice as routine, and from currently recruiting trials 29,30 . With the inexorable move towards increased FCC, we predict that an early facilitated cuddle between mothers and their extremely preterm babies will in time become standard care for most babies before NICU admission and, furthermore, will become expected by parents.…”

Section: Discussionmentioning

confidence: 99%

“…For the future, we believe that the recent pioneering studies in very preterm infants 16,29,30 pave the way for trials that must include extremely preterm infants. We speculate that eventually their first hour(s) of intensive care will be spent at the maternal bosom, their natural incubator.…”

Section: Conclusion and Futurementioning

confidence: 99%

Delivery room cuddles for extremely preterm babies and parents: concept, practice, safety, parental feedback

et al. 2021

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Aim Following extreme preterm birth, there has traditionally been felt an imperative to rush baby to the neonatal unit for ongoing intensive care. Immediate needs of parents to bond with their babies through direct early physical contact have often been overlooked; many weeks can pass before parents get to hold their babies for the first time. Recognition of the importance of early contact is growing. We aimed to review the safety and value of routinely practising delivery room cuddles for extremely preterm babies. Methods We reviewed delivery room cuddles in babies born <27 weeks’ gestation in our centre between 2006 and 2017 via case‐control. We also conducted a questionnaire survey of mothers who experienced a delivery room cuddle to gain their feedback and perspectives. Results We found no difference in age or temperatures on neonatal unit admission. There was no case of inadvertent extubation associated with cuddles. Parental feedback was very positive. Conclusion With appropriate safeguards, delivery room cuddles are feasible and achievable for extremely preterm babies irrespective of birth gestation. Facilitation of the cuddle is an early and very important family‐centred care practice which seems much appreciated by parents and which may improve bonding, lactation, and maternal mental health.

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“…However, this population could be an interesting target for skin-to-skin transfer. This topic has stimulated great interest, as two randomized controlled trials focusing on the assessment of early SSC with mothers during the extrauterine life adaptation of very preterm infants are ongoing 18,19 .…”

Section: Discussionmentioning

confidence: 99%

Potential benefits and pitfalls of skin-to-skin contact transport from birth room to neonatal unit

Clénet¹,

Carneiro²,

Jeanneaud³

et al. 2021

Preprint

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Background: Early and repeated skin-to-skin contact (SSC) between infants and their parents during neonatal hospitalization has positive effects on maternal bonding, breastfeeding, parent-child interactions and preterm infant neurodevelopmental outcomes.Purpose: Transfers through SSC of newborn infants requiring intensive care over 300 meters between the birth room and neonatal unit have been implemented since 2018. The safety of SSC transfer with the infant’s father was questioned when compared to the more common transfer method in incubators.Methods: Singletons born from May to December 2019 at our three-level maternity ward that required intensive neonatal care were eligible. The infants’ axillary temperature, heart rate, and oxygen need were reported at four timepoints during transfer in an incubator or through SSC and at 30 minutes after arrival in the neonatal unit. Infant characteristics, blood gas, glycemia, time-lapse between birth and first SSC in the unit and feeding modes were also reported.Results: Median gestational age was higher in the SSC group (incubator (n=54): 32 weeks vs SSC (n=57): 36 weeks, p=.003). All infants requiring mechanical ventilation were transported in an incubator. A decrease in temperature was observed during incubator installation in the SSC group (incubator: 0°C vs SSC: -0.2°C, p< .001), but the first SSC in the unit was earlier in this group (incubator: 22 h vs SSC: 11 h, p= .001 and p= .008 after adjustment for gestational age). Implications for practice: Although thermal stability was compromised, encouraging results regarding the first SSC in the unit promote the continuation of SSC transfers.

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Immediate parent-infant skin-to-skin study (IPISTOSS): study protocol of a randomised controlled trial on very preterm infants cared for in skin-to-skin contact immediately after birth and potential physiological, epigenetic, psychological and neurodevelopmental consequences

Cited by 30 publications

References 61 publications

Characterization of neonates born to mothers with SARS-CoV-2 infection: Review and meta-analysis

Characterization of neonates born to mothers with SARS-CoV-2 infection: Review and meta-analysis

Delivery room cuddles for extremely preterm babies and parents: concept, practice, safety, parental feedback

Potential benefits and pitfalls of skin-to-skin contact transport from birth room to neonatal unit

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