2009
DOI: 10.1016/j.ajem.2008.04.028
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Immediate prehospital hypothermia protocol in comatose survivors of out-of-hospital cardiac arrest

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Cited by 51 publications
(18 citation statements)
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“…Nineteen studies indicated that cooling could be initiated safely with IV ice-cold fluids (30 mL/kg of saline 0.9% or Ringer's lactate) (LOE 3 748,749,825,831,833,837 ; LOE 4 779,780,782-785,810,836,838 -843 ). Six studies indicated that cooling with IV cold saline can be initiated in the prehospital phase (LOE 1 781,844 ; LOE 2 845 ; LOE 3 261,846 748,841,850,[853][854][855]. Seven studies documented the use of ice packs (sometimes combined with wet towels) alone to induce and maintain hypothermia (LOE 2 823 ; LOE 3 824,828,830 ; LOE 4 847,849,856 ).…”
Section: Consensus On Sciencementioning
confidence: 99%
“…Nineteen studies indicated that cooling could be initiated safely with IV ice-cold fluids (30 mL/kg of saline 0.9% or Ringer's lactate) (LOE 3 748,749,825,831,833,837 ; LOE 4 779,780,782-785,810,836,838 -843 ). Six studies indicated that cooling with IV cold saline can be initiated in the prehospital phase (LOE 1 781,844 ; LOE 2 845 ; LOE 3 261,846 748,841,850,[853][854][855]. Seven studies documented the use of ice packs (sometimes combined with wet towels) alone to induce and maintain hypothermia (LOE 2 823 ; LOE 3 824,828,830 ; LOE 4 847,849,856 ).…”
Section: Consensus On Sciencementioning
confidence: 99%
“…[59] Several small randomized trials, and nonrandomized observational and retrospective trials, looked at prehospital cooling initiation for patients with OHCA with large-volume ice-cold (4°C) fluids (discussed in more detail in a separate chapter: Prehospital Therapeutic Hypothermia for Cardiac Arrest). [60][61][62][63][64][65][66][67][68] All these studies documented the safety and feasibility if ice-cold fluids for the rapid induction of therapeutic hypothermia. Other promising methods for induction of hypothermia include transnasal cooling device [69] , self-adhesive cooling pads [70] , and cranial cooling caps.…”
Section: Methods For Induction Of Therapeutic Hypothermiamentioning
confidence: 99%
“…Letztendlich könnte der Nutzen am größten sein, wenn bereits während des Kreislaufstillstands mit der Kühlung begonnen wird; Labordaten deuten darauf hin, dass dies den ROSC sogar erleichtert [754,755]. Verschiedene klinische Studien konnten zeigen, dass die Hypothermie präkli-nisch eingeleitet werden kann [511, 729,730,732,741], allerdings gibt es bis bisher keine klinischen Daten, die belegen, dass ein rasches Erreichen der Zieltemperatur zu einem besseren Outcome führt. In einer registerbasierten Fallserie mit 986 komatösen Patienten nach Kreislaufstill-stand war der Zeitpunkt des Kühlungs-beginns nicht mit einem besseren neurologischen Outcome nach Krankenhausentlassung assoziiert [666].…”
Section: Temperaturkontrolleunclassified