Immediate Repair Compared with Delayed Repair of Congenital Omphalocele: Short-Term Neonatal Outcomes in China

Na, Q; Liu, C; Cui, Huadong; Zhang, Z; Yin, Shou-Cheng; Li, Q

doi:10.1177/147323001103900634

Cited by 6 publications

(1 citation statement)

References 14 publications

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“…Acorroding an early study, it has been reported that patients with GO are less likely to undergo management with early closure compared with small omphalocele (12). In a study of omphalocele by Na et al (13), the immediate repair (IR group) was defined as undergoing surgery immediately after birth (usually less than 10 minutes), and after 3 hours of life, the surgical repair was defined as a late repair (control group). The children in the IR group started enteral nutrition earlier, had a lower infection rate, and had a shorter hospitalization time than those in the control group.…”

Section: Discussionmentioning

confidence: 99%

Surgical Treatment of Neonatal Giant Omphalocele in Delivery Room: A 10-Year Retrospective Study in East China

et al. 2019

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Background: The survival rate of neonatal giant omphaloceles has improved over the past 10 years, but the mortality rate remains at approximately 50% with traditional treatment. Delivery room surgery refers to a surgical procedure that is performed in the operating room to correct the structural defects of a newborn immediately after birth. Objectives: This study aimed to investigate the application of delivery room surgery for giant omphaloceles in East China. Methods: Neonates meeting the inclusion criteria of having omphalocele defects larger than 5 cm or of having most of the liver protruding into the sac were enrolled in this retrospective study. Data were evaluated specifically to determine the role of delivery room surgery in reducing the mortality of newborns with giant omphaloceles (GOs) and to identify factors that could optimize the conditions for traditional operations. A total of 52 newborns with GOs from two tertiary centres of paediatric surgery were identified. The patients were divided into two groups, the delivery room surgery group (group D) and the traditional operation group (group T), based on the perinatal management and time of surgery. Results: There was a significantly higher survival rate in the group D (77.8%) than in the group T (50%). The duration of ventilator use was 8.87 ± 10.12 days in the group D and 9.31 ± 7.75 days in the group T. The time of starting enteral nutrition was 12.88 ± 4.19 days in the group D and 16.75 ± 8.59 days in the group T. Newborns in the group T took more time to reach full enteral feeding. However, we did not find a significant difference in a comparison of the hospitalization time between the two groups (25.1 ± 18.1 days in the group D and 22.4 ± 11.1 days in the group T). Conclusions: The strategy of delivery room surgery appears to improve the survival of newborns with GOs and reduce family burden. A further reduction in mortality rates will depend on promoting the application of the delivery room surgical procedure.

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Section: Discussionmentioning

confidence: 99%

Surgical Treatment of Neonatal Giant Omphalocele in Delivery Room: A 10-Year Retrospective Study in East China

et al. 2019

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Are paediatric operations evidence based? A prospective analysis of general surgery practice in a teaching paediatric hospital

et al. 2014

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The present study shows that nowadays a remarkable number of paediatric surgical procedures are supported by high level of evidence. Despite this improvement in evidence-based paediatric surgical practice, more than a third of the procedures still lack sufficient evidence-based literature support. More RCTs are warranted to support and direct paediatric surgery practice according to the principals of EBM.

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The incidence of abdominal surgical site infections after abdominal birth defects surgery in infants: A systematic review with meta-analysis

Schattenkerk

Musters

Nijssen

et al. 2021

Journal of Pediatric Surgery

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Background: : Surgical site infections (SSI) are a frequent and significant problem understudied in infants operated for abdominal birth defects. Different forms of SSIs exist, namely wound infection, wound dehiscence, anastomotic leakage, post-operative peritonitis and fistula development. These complications can extend hospital stay, surge medical costs and increase mortality. If the incidence was known, it would provide context for clinical decision making and aid future research. Therefore, this review aims to aggregate the available literature on the incidence of different SSIs forms in infants who needed surgery for abdominal birth defects. Method: : The electronic databases Pubmed, EMBASE, and Cochrane library were searched in February 2020. Studies describing infectious complications in infants (under three years of age) were considered eligible. Primary outcome was the incidence of SSIs in infants. SSIs were categorized in wound infection, wound dehiscence, anastomotic leakage, postoperative peritonitis, and fistula development. Secondary outcome was the incidence of different forms of SSIs depending on the type of birth defect. Meta-analysis was performed pooling reported incidences in total and per birth defect separately. Results: : 154 studies, representing 11,786 patients were included. The overall pooled percentage of wound infections after abdominal birth defect surgery was 6% (95%-

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Immediate Repair Compared with Delayed Repair of Congenital Omphalocele: Short-Term Neonatal Outcomes in China

Cited by 6 publications

References 14 publications

Surgical Treatment of Neonatal Giant Omphalocele in Delivery Room: A 10-Year Retrospective Study in East China

Surgical Treatment of Neonatal Giant Omphalocele in Delivery Room: A 10-Year Retrospective Study in East China

Are paediatric operations evidence based? A prospective analysis of general surgery practice in a teaching paediatric hospital

The incidence of abdominal surgical site infections after abdominal birth defects surgery in infants: A systematic review with meta-analysis

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