Over the past decade, US states have responded to federal inaction on comprehensive immigration reform by increasing their output of immigrant policies, both beneficial and restrictive. Although there is a growing empirical literature focused on predicting such activity by states, less is known, especially on a broad scale, about the state-level consequences associated with the policy tone states adopt toward immigrants. To better understand the consequences of restrictive immigrant policies, we created a restrictive score for each state year between 2005 and 2014 and employed linear regression with panel-corrected standard errors to investigate effects on immigrant-related demographics, economic factors, and political participation. We found that states with higher restrictive policy tones do experience reductions in the number of foreign-born residents, including Hispanics and those with limited English proficiency, a goal of many state legislators who favor restrictive policies. States with restrictive policy tones showed reductions in unemployment and poverty rates as well, which are also professed goals for restrictive policy activity. Mediation analyses suggested that the effects of restrictive policy scores on economic conditions are indirect, being exerted through the percentage of a state's population that is foreign born. Finally, though much attention is focused on the expected increase in Latino political clout, restrictive policy tone was not predictive of increased voter registration or voting in states that pass these types of policies. If anti-immigrant policies are inducing those who oppose these policies to mobilize politically, it must be in an arena outside of voting.