Immobilization Techniques in the Fabrication of  Nanomaterial-Based Electrochemical Biosensors: A Review

Putzbach, William; Ronkainen, Niina J.

doi:10.3390/s130404811

Cited by 431 publications

(278 citation statements)

References 99 publications

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“…Unique characteristics at nanodimension makes them suitable for multiple applications such as bio sensing [1,2], photovoltaic, medicine [3], catalysis etc. Among these, metals with ultra-fine crystallite size with structural radius \100 nm showed considerable changes in mechanical, physical, and chemical properties in comparison with the bulk materials.…”

Section: Introductionmentioning

confidence: 99%

Effect of reaction parameters in synthesis, characterisation of electrodeposited zinc nanohexagons

Singaravelan¹,

Alwar²

2014

J Nanostruct Chem

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Nanocrystalline zinc was electrodeposited by reducing the Zn 2? ion from acid sulphate bath at room temperature. The effect of reaction parameters on the particle size, nature and spectral characteristics are deliberated. The surface morphology and texture of zinc nanoparticles (Zn NPs) were characterised by high resolution scanning electron microscopy (HR-SEM) and high resolution transmission electron microscopy (HR-TEM). SEM and TEM images showed the Zn NPs were in hexagonal structural morphology. Energy dispersive X-ray analysis reveals the chemical stoichiometry, and purity of the particles formed. The powder X-ray diffraction data indicates that the reflections of Zn NPs correspond hexagonal close packing structure with space group of P63/mmc. The line broadening was analysed by Debye-Scherrer equation and the average crystallite size of the zinc Nps synthesised at room temperature was in the range of 29 nm. WilliamsonHall analysis was used to study the contribution of crystallite size and lattice strain on the peak broadening. The surface plasmon resonance peak for the Zn NPs was observed near the blue shift with optical band gap of 3.38 eV. The influences of the current density, pH, additives, and concentration medium were analysed.

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Section: Introductionmentioning

confidence: 99%

Effect of reaction parameters in synthesis, characterisation of electrodeposited zinc nanohexagons

Singaravelan¹,

Alwar²

2014

J Nanostruct Chem

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“…A common feature of PPy sensing applications is the utilization of nanostructures like nanotubes and nanoparticles to increase the effective surface area. Also, enzymes, DNA or other biomolecules are used as dopants in order to increase sensor specificity [85][86][87][88]. Exploiting these resources, PPy has been used extensively for sensing of small metabolites like glucose, ascorbic acid and ammonia [89][90][91] but also for protein detection like haemoglobin [92] and prion protein [93].…”

Section: Sensorsmentioning

confidence: 99%

Organic Bioelectronic Tools for Biomedical Applications

2015

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Abstract:Organic bioelectronics forms the basis of conductive polymer tools with great potential for application in biomedical science and medicine. It is a rapidly growing field of both academic and industrial interest since conductive polymers bridge the gap between electronics and biology by being electronically and ionically conductive. This feature can be employed in numerous ways by choosing the right polyelectrolyte system and tuning its properties towards the intended application. This review highlights how active organic bioelectronic surfaces can be used to control cell attachment and release as well as to trigger cell signaling by means of electrical, chemical or mechanical actuation. Furthermore, we report on the unique properties of conductive polymers that make them outstanding materials for labeled or label-free biosensors. Techniques for electronically controlled ion transport in organic bioelectronic devices are introduced, and examples are provided to illustrate their use in self-regulated medical devices. Organic bioelectronics have great potential to become a primary platform in future bioelectronics. We therefore introduce current applications that will aid in the development of advanced in vitro systems for biomedical science and of automated systems for applications in neuroscience, cell biology and infection biology. Considering this broad spectrum of applications, organic bioelectronics could lead to timely detection of disease, and facilitate the use of remote and personalized medicine. As such, organic bioelectronics might contribute to efficient healthcare and reduced hospitalization times for patients. OPEN ACCESSElectronics 2015, 4 880

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“…PLA-b- (Putzbach & Ronkainen 2013). Certain properties of polymers, including stability, ease of synthesis, excellent tailorability, and good processability, also attracted many researchers' attention (Wang & Uchiyama 2013).…”

Section: Nanokomposit Polimer Bagi Pembangunan Biosensor Amperometrikmentioning

confidence: 99%

Comparative Study of Poly(4-vinylpyridine) and Polylactic Acid-block-poly (2-vinylpyridine) Nanocomposites on Structural, Morphological and Electrochemical Properties

Long¹,

Azmi²,

Kim³

et al. 2017

JSM

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Polymer-based nanocomposites have attracted a lot of attention for amperometric biosensor development due to their general physical and chemical properties including biocompatibility, film-forming ability, stability and different functional groups that can be bonded with other biomolecues. In this study, poly-4-vinlyridine homopolymer (P4VP) and polylactic acid-block-poly(2-vinylpyridine) block copolymer Nanokomposit polimer bagi pembangunan biosensor amperometrik menarik banyak perhatian kerana sifat fizikal dan kimia am mereka termasuk keserasian-bio, keupayaan pembentukan filem, kestabilan dan bergantung kepada kumpulan berfungsi yang berkemampuan untuk terikat dengan biomolekul lain. Dalam kajian ini, poli-4-vinilpiridin (P4VP) dan polilaktik asid-blok-poly (2-vinilpiridin) (PLA-b-P2VP) telah digunakan untuk dihibridkan dengan prekursor emas berdasarkan gabungan antara nitrogen kumpulan piridin daripada P4VP atau P2VP blok dengan prekursor emas (Au 3+

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Immobilization Techniques in the Fabrication of Nanomaterial-Based Electrochemical Biosensors: A Review

Cited by 431 publications

References 99 publications

Effect of reaction parameters in synthesis, characterisation of electrodeposited zinc nanohexagons

Effect of reaction parameters in synthesis, characterisation of electrodeposited zinc nanohexagons

Organic Bioelectronic Tools for Biomedical Applications

Comparative Study of Poly(4-vinylpyridine) and Polylactic Acid-block-poly (2-vinylpyridine) Nanocomposites on Structural, Morphological and Electrochemical Properties

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