Immune checkpoint inhibitor-associated myocarditis and coronary artery disease: There may be more than meets the eye!

Maria, A.; Delmas, Clément; Coustal, Cyrille; Palassin, Pascale; Roubille, François

doi:10.1016/j.ejca.2022.09.028

European Journal of Cancer

2022

DOI: 10.1016/j.ejca.2022.09.028

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Immune checkpoint inhibitor-associated myocarditis and coronary artery disease: There may be more than meets the eye!

A. Maria

Clément Delmas

Cyrille Coustal

et al.

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A comprehensive review on immune checkpoint inhibitors induced cardiotoxicity characteristics and associated factors

lessomo,

Mandizadza,

Mukuka

et al. 2023

Eur J Med Res

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Newly approved cancer drugs called ICIs have shown remarkable success in improving patient survival rates, but they also have the potential for inflammatory and immune-related side effects, including those affecting the cardiovascular system. Research has been conducted to understand the development of these toxicities and identify risk factors. This review focuses on the characteristics of ICI-induced cardiotoxicity and discusses the reported risk factors. It is important for cardio-oncologists to understand the basic concepts of these drugs to better understand how cardiotoxicities occur. It might be hard to find reports, where all patients treated with ICIs had developed cardiac toxicity, because there could be other existing and variable factors that influence the likelihood or risk of developing cardiotoxicity during treatment. Various clinical parameters have been explored as potential risk factors, and further investigation is needed through large-scale studies.

show abstract

A comprehensive review on immune checkpoint inhibitors induced cardiotoxicity characteristics and associated factors

lessomo,

Mandizadza,

Mukuka

et al. 2023

Eur J Med Res

View full text Add to dashboard Cite

show abstract

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Immune checkpoint inhibitor-associated myocarditis and coronary artery disease: There may be more than meets the eye!

Cited by 1 publication

References 10 publications

A comprehensive review on immune checkpoint inhibitors induced cardiotoxicity characteristics and associated factors

A comprehensive review on immune checkpoint inhibitors induced cardiotoxicity characteristics and associated factors

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