2024
DOI: 10.1001/jamaoncol.2023.5269
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Immune Checkpoint Inhibitor Therapy Before Nephrectomy for Locally Advanced and Metastatic Renal Cell Carcinoma

Alireza Ghoreifi,
Ulka Vaishampayan,
Ming Yin
et al.

Abstract: ImportanceThe therapeutic landscape of advanced renal cell carcinoma (RCC) has rapidly evolved in the past 2 decades, with the advent of cytokines therapy followed by targeted therapies and novel immune checkpoint inhibitors (ICI). This article aims to review the current evidence and ongoing trials of neoadjuvant or prenephrectomy ICI therapy in patients with locally advanced and metastatic RCC.ObservationsA literature search was performed using the Cochrane Central Register of Controlled Trials, ClinicalTrial… Show more

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Cited by 7 publications
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