Immune‐dysregulation harnessing in myeloid neoplasms
Mohammad Jafar Sharifi,
Ling Xu,
Nahid Nasiri
et al.
Abstract:Myeloid malignancies arise in bone marrow microenvironments and shape these microenvironments in favor of malignant development. Immune suppression is one of the most important stages in myeloid leukemia progression. Leukemic clone expansion and immune dysregulation occur simultaneously in bone marrow microenvironments. Complex interactions emerge between normal immune system elements and leukemic clones in the bone marrow. In recent years, researchers have identified several of these pathological interactions… Show more
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