Immune response to split-product influenza vaccine in preterm and full-term young children

Groothuis, Jessie R.; Levin, Myron J.; Lehr, Marsha V.; Weston, Janet A.; Hayward, Anthony R.

doi:10.1016/0264-410x(92)90156-e

Cited by 39 publications

(16 citation statements)

References 9 publications

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“…64 Immunogenicity is inconsistent and generally poor in infants younger than 6 months. 65,66 It has been shown repeatedly that seroresponse rates of antibody to HA increase with increasing age of the group immunized, ranging from 70% to 100% among adolescents. 44,46,67 Children younger than 9 years are less likely to have been primed by natural infection and thus are recommended to receive 2 doses 4 weeks apart the first season they are immunized.…”

Section: Immunogenicity Of Tivmentioning

confidence: 99%

Technical Report: Reduction of the Influenza Burden in Children

Rennels¹,

Meissner²

2002

Pediatrics

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ABSTRACT. Epidemiologic studies have shown that children of all ages with certain chronic conditions, such as asthma, and otherwise healthy children younger than 24 months (6 through 23 months) are hospitalized for influenza and its complications at high rates similar to those experienced by the elderly. Annual influenza immunization is already recommended for all children 6 months and older with high-risk conditions. By contrast, influenza immunization has not been recommended for healthy young children. To protect children against the complications of influenza, increased efforts are needed to identify and recall high-risk children. In addition, immunization of children between 6 through 23 months of age and their close contacts is now encouraged to the extent feasible. Children younger than 6 months may be protected by immunization of their household contacts and out-of-home caregivers. The ultimate goal is universal immunization of children 6 to 24 months of age.

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Section: Immunogenicity Of Tivmentioning

confidence: 99%

Technical Report: Reduction of the Influenza Burden in Children

Rennels¹,

Meissner²

2002

Pediatrics

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“…En prematuros con enfermedad pulmonar crónica se ha demostrado que, si bien la inmunidad celular está reducida, estos niños producen anticuerpos suficientes para alcanzar protección contra las tres cepas de virus influenza contenidas en la vacuna 15 .…”

Section: Vacunación Anti-influenzaunclassified

Vacunación del niño prematuro: Un tema a veces olvidado

2005

Rev. chil. infectol.

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“…Premature infants make lower antibody responses to influenza (1,2) and tetanus (3,4) immunization during their first 2 y of life compared with age-matched children born at full term. This finding may be clinically relevant because premature infants have an increased mortality and morbidity from virus infections of the respiratory tract compared with infants born at full term (5,6).…”

mentioning

confidence: 98%