Immune system cells as biomarkers in the diagnostics of endometriosis

Popova, Olga

doi:10.17116/repro2019250218

Probl. reprod.

2019

DOI: 10.17116/repro2019250218

|View full text |Cite

Immune system cells as biomarkers in the diagnostics of endometriosis

Olga Popova¹

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2021

2022

Publication Types

Select...

Article4

Relationship

Self Cite0

Independent4

Authors

Journals

Cited by 4 publications

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

The Value of Peripheral Blood Nk Cellsand Expression of Transforming Growth Factor Beta-1 in Recurrent Ovarianendometriosis

Petrovskaya¹,

Pechenikova²

2022

Journal of VolgSMU

View full text Add to dashboard Cite

Affiliation. Federal state budgetary educational institution of higher education «North-Western State Medical University named after I. I. Mechnikov» under the Ministry of Health of the Russian Federation, Saint-Petersburg Introduction. Elevated level of transforming growth factor-61 (TGF-61) can be the cause of impaired immune response among women with endometriosis due to its ability to reduce the activity of NK-cells, which contributes to the survival of ectopic endometrial cells in the abdominal cavity and plays a key role in the progression of the disease. Materials and methods. 196 endometrioma observations were studied, an immunological study of peripheral blood was performed with the determination of CD3-CD16/56+ (natural killers) and an IHC study of the expression of TGF-61 in the capsule of an endometrioid cyst and in a preserved cytogenic stroma. The IHC study showed that the expression area of TGF-61 was significantly larger in the surgical material in the recurrent course of endometriosis; an immunological study revealed a significant decrease in NKcells during the endo-metrioma recurrence. Conclusion: Further study of the relationship between TGF-61 and NK cells may be important as prognostic markers of recurrent endometriosis.

show abstract

The Value of Peripheral Blood Nk Cellsand Expression of Transforming Growth Factor Beta-1 in Recurrent Ovarianendometriosis

Petrovskaya¹,

Pechenikova²

2022

Journal of VolgSMU

View full text Add to dashboard Cite

show abstract

The role of the immune system in the pathogenesis of endometriosis

et al. 2021

View full text Add to dashboard Cite

The review presents a critical analysis of data on the role of immune factors in the pathogenesis of endometriosis. The research results accumulated by now convincingly demonstrate that an abnormal subclinical inflammatory response and disorders in the immune control system play a significant role in the onset, progression and persistence of endometriosis. In spite of the fact that many studies are concentrates on particular components of immune disorders in the pathogenesis of endometriosis, there is still no overall picture summarizing these data. Further research is needed to find immunological parameters that can be used as markers for clinical use in non-invasive diagnosis of this disease. The search for specific immune markers that could be used for target immunotherapy of endometriosis also remains relevant.

show abstract

Endometrioid disease is a modern view of the problem

Schmidt

Gaivoronskikh

Kremlev

et al. 2022

jour

View full text Add to dashboard Cite

The article provides a review of specialized literature in order to generalize and systematize data on modern ideas about endometrioid disease in the clinical practice of doctors of various specialties. The social signifi cance of this disease is indicated. The article refl ects the main modern ideas about etiology and pathogenesis of endometriosis. Although there are a number of issues, they are not studied completely. The crucial role of the immune system malfunction in the formation of endometrioid disease is highlighted. The genetic ideas about the development of endometriosis are refl ected. Modern approaches to the treatment of endometriosis and the place of cholecalciferol in modern complex therapy of endometriosis are presented.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Immune system cells as biomarkers in the diagnostics of endometriosis

Cited by 4 publications

References 39 publications

The Value of Peripheral Blood Nk Cellsand Expression of Transforming Growth Factor Beta-1 in Recurrent Ovarianendometriosis

The Value of Peripheral Blood Nk Cellsand Expression of Transforming Growth Factor Beta-1 in Recurrent Ovarianendometriosis

The role of the immune system in the pathogenesis of endometriosis

Endometrioid disease is a modern view of the problem

Contact Info

Product

Resources

About