Immunity against COVID-19: Potential role of Ayush Kwath

Shankar, Gautam; Gautam, Arun; Chhetri, Sahanshila; Bhattarai, Urza

doi:10.1016/j.jaim.2020.08.003

Cited by 99 publications

(62 citation statements)

References 52 publications

(64 reference statements)

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“…The qualitative appraisal of the analyzed data reflects that a considerable majority of the respondents benefitted from the use of AYUSH measures, which were either traditional formulations with centuries of use in the maintenance of health or home remedies and are an integral part of Indian culture and cuisine. Due to the long history of use of many herbal remedies and the experiences that have passed from generation to generation, people are relying on herbal remedies and some simple home remedies for common diseases that are used across India irrespective of sociocultural, religious, and geographical differences [ 31 ]. The use of AYUSH measures is likely to evoke a positive response to the psychological and physical well-being of the respondents [ 32 ].…”

Section: Discussionmentioning

confidence: 99%

Mobile App–Reported Use of Traditional Medicine for Maintenance of Health in India During the COVID-19 Pandemic: Cross-sectional Questionnaire Study

Srikanth¹,

Rana²,

Singhal³

et al. 2021

JMIRx Med

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Background India follows a pluralistic system for strategic and focused health care delivery in which traditional systems of medicine such as Ayurveda, yoga and naturopathy, Unani, Siddha, Sowa Rigpa, and homoeopathy (AYUSH) coexist with contemporary medicine, and this system functions under the Ministry of AYUSH (MoA). The MoA developed a mobile app, called AYUSH Sanjivani, to document the trends of the use of AYUSH-based traditional and holistic measures by the public across India. Analysis of the data generated through this app can help monitor the extent of the use of AYUSH measures for maintenance of health during the COVID-19 pandemic and aid effective health promotion and communication efforts focused on targeted health care delivery during the pandemic. Objective The purpose of the study was to determine the extent of use of AYUSH measures by the public in India for maintenance of health during the COVID-19 pandemic as reported through the AYUSH Sanjivani mobile app. Methods Cross-sectional analysis of the data generated through the Ayush Sanjivani app from May 4 to July 31, 2020, was performed to study the pattern and extent of the use of AYUSH-based measures by the Indian population. The responses of the respondents in terms of demographic profile, use pattern, and benefits obtained; the association between the use of AYUSH-based measures and symptomatic status; and the association between the duration of use of AYUSH-based measures and the outcome of COVID-19 testing were evaluated based on bivariate and multivariate logistic regression analysis. Results Data from 723,459 respondents were used for the analysis, among whom 616,295 (85.2%) reported that they had been using AYUSH measures for maintenance of health during the COVID-19 pandemic. Among these 616,295 users, 553,801 (89.8%) either strongly or moderately agreed to have benefitted from AYUSH measures. Ayurveda and homeopathic measures and interventions were the most preferred by the respondents across India. Among the 359,785 AYUSH users who described their overall improvement in general health, 144,927 (40.3%) rated it as good, 30,848 (8.6%) as moderate, and 133,046 (40.3%) as slight. Respondents who had been using AYUSH measures for less than 30 days were more likely to be COVID-19–positive among those who were tested (odds ratio 1.52, 95% CI 1.44-1.60). The odds of nonusers of AYUSH measures being symptomatic if they tested positive were greater than those of AYUSH users (odds ratio 4.01, 95% CI 3.61-4.59). Conclusions The findings of this cross-sectional analysis assert that a large proportion of the representative population practiced AYUSH measures across different geographic locations of the country during the COVID-19 pandemic and benefitted considerably in terms of general well-being, with a possible impact on their quality of life and specific domains of health.

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Section: Discussionmentioning

confidence: 99%

Mobile App–Reported Use of Traditional Medicine for Maintenance of Health in India During the COVID-19 Pandemic: Cross-sectional Questionnaire Study

Srikanth¹,

Rana²,

Singhal³

et al. 2021

JMIRx Med

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“…These antioxidant medicinal herbs not only have the capability to modulate immune system with downregulation of proinflammatory cytokines but also have antiviral properties to directly inhibit viral proteins and viral replication machinery [4] , [207] , [208] . Further, these herbs are generally administered in the form of polyherbal formulations [209] (Ayurveda/TCM) or herbo-mineral formulations [210] (Siddha) or homeopathic dilutions [211] . The polyherbal formulations have multiple components in micromolar concentration which work together in a synergistic manner [212] to suppress the production of nitric oxide, prostaglandin E2, IL-6, IL1β, phosphorylations of mitogen-activated protein (MAP) kinases, including extracellular signal-regulated kinase (ERK) [213] .…”

Section: Potential Therapeutic Approachesmentioning

confidence: 99%

Therapeutic approaches for SARS-CoV-2 infection

Gupta¹,

Pradhan²,

Maurya

et al. 2021

Methods

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“…For herbs that contains the same effective formulas as QC and HQC, Vit D and Zinc QC, or HQC + Vit D + Zinc+anticoagulant+cortisone+breath aid (such as with the nebulizers) have proved very high cure percentage of infections in early and mid-stages of COVID-19 (Anonymous reviewer). Various reviews on COVID-19 and immunity boosting with the use of herbs have appeared [55]. Immunomodulatory effects of medicinal plants such as Tulsi / Ocimum sanctum, Cinnamomum zeylanicum, Zingiber officinale and Piper nigrum know since ancient time and has also been accepted by science, when these plants bear medicinal and cultural values.…”

Section: Herbal Treatmentsmentioning

confidence: 99%

Insights of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) pandemic: a current review

Choudhary

Dheeman²,

Sharma

et al. 2021

Biol Proced Online

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COVID-19, a pandemic of the 21st century caused by novel coronavirus SARS-CoV-2 was originated from China and shallowed world economy and human resource. The medical cures via herbal treatments, antiviral drugs, and vaccines still in progress, and studying rigorously. SARS-CoV-2 is more virulent than its ancestors due to evolution in the spike protein(s), mediates viral attachment to the host’s membranes. The SARS-CoV-2 receptor-binding spike domain associates itself with human angiotensin-converting enzyme 2 (ACE-2) receptors. It causes respiratory ailments with irregularities in the hepatic, nervous, and gastrointestinal systems, as reported in humans suffering from COVID-19 and reviewed in the present article. There are several approaches, have been put forward by many countries under the world health organization (WHO) recommendations and some trial drugs were introduced for possible treatment of COVID-19, such as Lopinavir or Ritonavir, Arbidol, Chloroquine (CQ), Hydroxychloroquine (HCQ) and most important Remdesivir including other like Tocilizumab, Oritavancin, Chlorpromazine, Azithromycin, Baricitinib, etc. RT-PCR is the only and early detection test available besides the rapid test kit (serodiagnosis) used by a few countries due to unreasonable causes. Development of vaccine by several leader of pharmaceutical groups still under trial or waiting for approval for mass inoculation. Management strategies have been evolved by the recommendations of WHO, specifically important to control COVID-19 situations, in the pandemic era. This review will provide a comprehensive collection of studies to support future research and enhancement in our wisdom to combat COVID-19 pandemic and to serve humanity.

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Immunity against COVID-19: Potential role of Ayush Kwath

Cited by 99 publications

References 52 publications

Mobile App–Reported Use of Traditional Medicine for Maintenance of Health in India During the COVID-19 Pandemic: Cross-sectional Questionnaire Study

Mobile App–Reported Use of Traditional Medicine for Maintenance of Health in India During the COVID-19 Pandemic: Cross-sectional Questionnaire Study

Therapeutic approaches for SARS-CoV-2 infection

Insights of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) pandemic: a current review

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