Immunity study among burn patients infected with bacterial pseudomonas species

Abstract

The Invade of the Burns infaction by potentially pathogenic bacteria constitutes threatens its transmission to different human tissues and organs, this study provides isolation and identification of 37 isolates bacteria pseudomonas species for the 120 specimen (20 pseudomonas.aeruginosa.10 Pseudomonas. fluorescens.7 Pseuomonas.putadia) recovered from burn infections. In this study, some of virulence factors were detected by traditional phenotypic methods. The results Bacterial gelatinase . The results of the study demonstrated that the high production of gelatinase was released from P.aeruginosa 20/20(100%, P.fluorescens10/10(100%).p putedia 5/7(71.42%) . the total pseudomonas spp 35/37(94.59%) isolates . The results haemolysin production In the blood agar plate method, 30/37 (80.08%) of 20/20(100%) P. aeruginosa.9/10(90%) p. fluorescens. and 1/7(14.28%) p.putedia of all isolates demonstrate beta-hemolytic activity. Total and Deferential Count of White Blood Cells the results of WBC and differential cells. The results of WBC and differential count of neutrophils and monocytes in survivors burn patients have shown the significant increase (P<0.05) compared to control group. But the lymphocytes,eosinophils and basophils showed non-significant (P>0.05). Cytokines Detections Interleukin-6 the concentration of IL-6 in burn patients were of significant elevation (P<0.01) in compared to control group, yet the concentration of IL-6 showed a highly elevation burn patients.

Genetic Relationship Between Chronic Otitis Media Infection And TLR4 Gene In AL-Qadisyah province, Iraq .

“…Overaӏӏ, the study suggests that genetic variations in TLR2 and TLR4 genes may play a role in determining susceptibiӏity to chronic otitis media. However, more research is needed to further understand the specific impact of these genetic variations on the development and progression of different forms of otitis media.. [15,16], it was found that a singӏe nucӏeotide poӏymorphism (SNP) caӏӏed rs5030717 (A/G) ӏocated in the third intron of the TLR4 gene was significantӏy associated with an increased risk of otitis media (OM). The minor aӏӏeӏe G of this SNP was identified as a risk factor, with an odds ratio (OR) of 1.33 and a p-vaӏue of 0.003.…”