Immuno-PET and Targeted α-Therapy Using Anti–Glypican-1 Antibody Labeled with⁸⁹Zr or²¹¹At: A Theranostic Approach for Pancreatic Ductal Adenocarcinoma

Glypican-1-targeted antibody–drug conjugate inhibits the growth of glypican-1-positive glioblastoma

“…1 A). Our group has also previously demonstrated that a radioactively labeled humanized anti-GPC1 antibody (clone T2) rarely transfers to a normal mouse brain [32] . Furthermore, GPC1 was also infrequently expressed in normal tissue [33] .…”