1991
DOI: 10.1007/978-3-642-76074-7_9
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Immunochemistry of Candida Mannans

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Cited by 23 publications
(16 citation statements)
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“…Candida albicans strains were divided into two serotypes, A and ~, by Hasenclever and Mitchell [3] from the antigenicity of cell vall mannans. A structural study of the mannans of the 2 albicans serotype A and B strains has been achieved during he last several years [4,5], and we have demonstrated the pres-'nce of phosphodiesterified fl-l,2-1inked oligomannosyl moieies as a group of common epitopes throughout the two seroype strains [6,7]. The major difference between the structural !eatures of mannans from C. albicans serotype A and B strain .…”
mentioning
confidence: 89%
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“…Candida albicans strains were divided into two serotypes, A and ~, by Hasenclever and Mitchell [3] from the antigenicity of cell vall mannans. A structural study of the mannans of the 2 albicans serotype A and B strains has been achieved during he last several years [4,5], and we have demonstrated the pres-'nce of phosphodiesterified fl-l,2-1inked oligomannosyl moieies as a group of common epitopes throughout the two seroype strains [6,7]. The major difference between the structural !eatures of mannans from C. albicans serotype A and B strain .…”
mentioning
confidence: 89%
“…The biosynthetic pathway of the serotype A-specific side chain can be depicted as shown in Fig. 1 based on the structural analysis findings of C. albicans mannans [4]. Namely, the first transfer of the fl-l,2-linked mannose unit from GDP-mannose to the non-reducing terminal site of the ~-l,2-1inked mannotetraosyl side chain takes place by participation of the fl-l,2-ManTase I.…”
Section: ~ Introductionmentioning
confidence: 99%
“…FAb 6, genic yeasts, have been investigated for use as the target antiwhich recognizes [3-1,2-1inked mannose residue [4], was used as a negative control. Sera were diluted from 9-to 19683-fold with phosgen in diagnosing invasive candidiasis [6]. Although [3-1,2-phate-buffered saline containing 0.1% (w/v) Tween 20 (PBST).…”
Section: Preparation Ofmannans Munochemical Relationship Among Clinicmentioning
confidence: 99%
“…Manetl---~3Manal--*2Manc~l--*2Manctl 6 the inner c~-l,2-1inked oligomannosyl unit. M5-3,6 did not Man inhibit under the same conditions, indicating that FAb 34…”
Section: M53mentioning
confidence: 99%
“…We have studied the structures of the cell wall mannans of medically important Candida species for several years (1)(2)(3) and demonstrated that there are three types of ␤-1,2 linkagecontaining side chains in its cell wall mannans. One is the ␤-1,2-linked mannooligomer, which is located in a phosphodiesterified oligosaccharide moiety, as the common epitope in the mannans of several Candida species (4 -9).…”
mentioning
confidence: 99%