Immunocytological study of the chronology of pituitary cytogenesis in the domestic pig (Sus scrofa) with special reference to the functioning of the hypothalamo-pituitary-gonadal axis

Danchin, Étienne; Dubois, M. P.

doi:10.1051/rnd:19820111

Cited by 32 publications

(29 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…LH cells were detected earlier than FSH and LH-FSH cells. This finding is in agreement with previous work in pig [6,7,22], rat [23][24][25][26], and sheep fetuses [27].…”

Section: Discussionsupporting

confidence: 95%

Heterogeneity in the Storage of Gonadotropins in the Ovine Fetus and Evidence for Luteinizing Hormone-Follicle-Stimulating Hormone Cells in the Fetal Pituitary

Messaoud-Toumi¹,

Taragnat²,

Durand³

1993

Biology of Reproduction

View full text Add to dashboard Cite

In this immunocytochemical study, heterogeneity in the storage of gonadotropins in the sheep fetus was investigated. LH cells were first detected at 50 days of gestation, whereas FSH and LH-FSH cells were observed from Day 89 on; no gonadotropes containing ACTH were observed. LH cell percentage increased for both sexes between 99 and 120 days of gestation (from 2.8 +/- 0.1 to 4.0 +/- 0.3), remained high until term, and did not change after birth. In males, FSH cell percentages increased about twofold between 120 and 130 days to 4.0 +/- 0.4, fell at 140 days to 1.6 +/- 0.1, and then increased in the newborn lambs about twofold. A similar pattern of development was observed in females, but the percentages were lower than in males. LH-FSH cell percentages increased about twofold in males between 99 and 120 days of gestation to 1.1 +/- 0.1, decreased to 0.8 +/- 0.1 at 140 days, then increased about twofold in newborn lambs. In the 99-day-old females, this percentage was 0.5 +/- 0.1; it remained stable between 99 days of fetal life and term and did not change after birth. Hence, the pattern of change in the percentages of these cells appeared to be similar to that of LH cells and different from that of FSH cells. This suggests that LH-FSH cells might result from a shift of monohormonal cells to bihormonal cells. However, these cells seem to be regulated differently in male and female fetuses, and this suggests that they possess a specific role during ontogenesis.

show abstract

“…LH cells were detected earlier than FSH and LH-FSH cells. This finding is in agreement with previous work in pig [6,7,22], rat [23][24][25][26], and sheep fetuses [27].…”

Section: Discussionsupporting

confidence: 95%

Heterogeneity in the Storage of Gonadotropins in the Ovine Fetus and Evidence for Luteinizing Hormone-Follicle-Stimulating Hormone Cells in the Fetal Pituitary

Messaoud-Toumi¹,

Taragnat²,

Durand³

1993

Biology of Reproduction

View full text Add to dashboard Cite

show abstract

“…By contrast, ACTH-immunoreactive cells are the first immunoreactive cells in fetal mammals, such as the human [Baker and Jaffe, 1975], rat [Sétá ó and Nakane, 1972;Chatelain et al, 1979;Watanabe and Daikoku, 1979;Nemeskéri et al, 1988], pig [Danchin and Dubois, 1982;Dacheux, 1984a, b, Sasaki et al, 1992, and dog [Sasaki and Nishioka, 1998]. The fetus of mammals might need ACTH from earlier stages than that of the chicken, because of the relief of stress from the mother.…”

Section: Discussionmentioning

confidence: 99%

Embryonic Development of the Pituitary Gland in the Chick

Sasaki

Doshita²,

Matsumoto³

et al. 2003

Cells Tissues Organs

View full text Add to dashboard Cite

Pituitary glands of chicken, from stages 20 (70 ∼ 72 h of incubation) to 46 (20 days) of Hamburger and Hamilton (1951), were studied by immunocytochemical and histological stainings and India ink injection into blood vessels. Using the distribution pattern of 6 types of immunoreactive adenohypophyseal cells and the location of pituitary stalk as guideposts, we found how specific areas in the epithelium of Rathke’s pouch differentiate into specific regions of the adenohypophysis at 20 days. In the sagittal plane, the walls of Rathke’s pouch were tentatively divided into the upper part (A₁ + A₂) and lower part (A₃) of the anterior wall, and the posterior wall (P₁ + P₂ + P₃). The cephalic lobe was mainly assembled by the proliferation of parenchymal cells in the areas A₂ + A₃ + P₂ of Rathke’s pouch epithelia at 3 days of incubation. The caudal lobe was derived from A₁ + P₁ + P₃. The pars tuberalis was derived from A₁ + A₂. Thus, the avian adenohypophysis is established at 13 days, though the blood supply to the pars distalis is established at 20 days. Therefore, the cephalic lobe and caudal lobe of the pars distalis and the pars tuberalis of the chicken adenohypophysis are derived from specific areas of the cell cords of Rathke’s pouch at 3 days of incubation.

show abstract

“…[1,9,18], and detectable levels of plasma LH and FSH have been observed as early as Day 60 p.c. [1].…”

Section: Introductionmentioning

confidence: 96%

Ontogeny of Gonadal Luteinizing Hormone and Follicle-Stimulating Hormone Receptors in the Fetal Pig and Related Changes in Gonadotropin and Testosterone Secretion1

Goxe¹,

Prunier²,

Rémy³

et al. 1993

Biology of Reproduction

View full text Add to dashboard Cite

Fetuses of Large White and Meishan sows were collected at 28, 35, 49, 56, 75, 90, 103, and 113 days of gestation. LH, FSH, and testosterone concentrations were measured either in amniotic fluid (Days 28-56) or in arterial umbilical blood (Days 75-113). Gonads were analyzed for their content of LH and FSH receptors and RNA transcripts. Most of these parameters were similar in the two breeds, except that the mean testosterone concentration was higher (p < 0.05) in the plasma of 75-113-day Meishan fetuses (309 and 136 pg/ml in males and females, respectively) than in Large White fetuses (152 and 109 pg/ml). Higher testosterone concentrations were detected in males than in females, either in amniotic fluid (114 vs. 81 pg/ml, p < 0.05) or in plasma (230 vs. 122 pg/ml, p < 0.01). In contrast, higher gonadotropin concentrations were found in the plasma of females than in that of males (2 vs. 1.6 ng/ml LH and 4.2 vs. 1.4 ng/ml FSH, p < 0.05). In the testis, 2-3 pmol/g gonad of LH and FSH receptors were detected as early as Day 28. This value increased to 10-13 pmol/g between 35 and 56 days before declining to 3-5 pmol/g after Day 90. In ovaries, LH receptors were detected in the earlier period (Days 28-56) at 1-3 pmol/g before diminishing to 0.1-0.4 pmol/g. FSH receptors were higher at Day 28 (1 pmol/g) than at any subsequent stage (0.1-0.4 pmol/g). The gonadal content of RNA transcripts was significantly higher in testes than in ovaries.(ABSTRACT TRUNCATED AT 250 WORDS)

show abstract

Immunocytological study of the chronology of pituitary cytogenesis in the domestic pig (Sus scrofa) with special reference to the functioning of the hypothalamo-pituitary-gonadal axis

Cited by 32 publications

References 22 publications

Heterogeneity in the Storage of Gonadotropins in the Ovine Fetus and Evidence for Luteinizing Hormone-Follicle-Stimulating Hormone Cells in the Fetal Pituitary

Heterogeneity in the Storage of Gonadotropins in the Ovine Fetus and Evidence for Luteinizing Hormone-Follicle-Stimulating Hormone Cells in the Fetal Pituitary

Embryonic Development of the Pituitary Gland in the Chick

Ontogeny of Gonadal Luteinizing Hormone and Follicle-Stimulating Hormone Receptors in the Fetal Pig and Related Changes in Gonadotropin and Testosterone Secretion1

Contact Info

Product

Resources

About