Immunoelektrophoretische Untersuchungen im Serum Rheumakranker

Levels of serum immunoglobulins in patients with rheumatoid arthritis.

“…The inconstant or absent accentuation of the precipitation line corresponding to yM fraction is noteworthy. In contrast with the observations of Cleve (1958), Mackiewicz andFenrych (1961,) Zanussi, Invernizzi, del Giacco, andLuporini (1961), Caronia, Martelli, and Pitucco (1962), and Sfikakis and Loukopoulos (1964), our results appear to agree with the data of Francq, Eyquem, Podliachouk, and Jacqueline (1959), Podliachouk, Francq, Eyquem, and Jacqueline (1960), Eyquem, Jacqueline, Podliachouk, and Francq (1960), and Fallet, Meyer, and Scheidegger (1961), who think that immuno-electrophoretic analysis of rheumatoid sera is not able to reveal a significant increase of yM. It may sometimes be possible to find a very marked increase of yM in sero-negative patients and in some healthy controls, but an increase of this fraction was not observed in sero-positive cases.…”