Immunofluorescence in oral lesions

Nithya, S; Sankarnarayanan, R; Hemalatha, V.T.; Sarumathi, T.

doi:10.4103/jomfp.jomfp_207_17

Cited by 3 publications

(2 citation statements)

References 6 publications

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“…These methods supplement the clinical findings and histopathology for the diagnosis of immunobullous disorders. When the antigen reacts directly with a fluorescein-conjugated antibody specific for the material sought within the tissue, it is called as the direct technique, while indirect immunofluorescence is a twostep serological procedure for detecting the circulating antibodies in the body fluids [21].…”

Section: Apoptolysis Theorymentioning

confidence: 99%

Revisiting pemphigus vulgaris: A case report and review of literature

Nimish Deo,

Shailesh Deshmukh

2023

Int J Case Rep Images

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Introduction: Pemphigus is an autoimmune blistering mucocutaneous disease. Production of auto-antibodies against desmosomal glycoproteins is a characteristic feature of the disease. Oral lesions of pemphigus vulgaris are many a times first sign of the disease and hence it is important for a dentist to be familiar with the clinical appearance, diagnosis, and treatment modalities. Case Report: This report describes a case of pemphigus vulgaris in a female patient who presented with ulcers on the gingiva. On the basis of clinical examination and histopathology, we arrived at a diagnosis of pemphigus vulgaris, which was confirmed by immunofluorescence. Conclusion: If left undiagnosed or untreated pemphigus vulgaris may be fatal. Early diagnosis will aid in appropriate treatment and better outcome of the disease.

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Section: Apoptolysis Theorymentioning

confidence: 99%

Revisiting pemphigus vulgaris: A case report and review of literature

Nimish Deo,

Shailesh Deshmukh

2023

Int J Case Rep Images

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“…In indirect immunofluorescent assay, the secondary fluorescein-conjugated antibody reacted with primary antigen-antibody complex. 4 Flow Cytometry: It is also known as Cytofluorography. It allows detection of single or multiple microbes in plaque samples, based on their atypical cytometric parameters.…”

Section: Introductionmentioning

confidence: 99%

Microbiological Aids in Periodontics

Soumya Ranjan Panda

2020

Indian Journal of Forensic Medicine & Toxicology

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New approaches to periodontal diagnosis, including advanced microbiologic, biochemical, and genetic tests, have been shown to provide the clinician with the information not available by traditional means. The purpose of a diagnostic test is to confirm, exclude, classify, or monitor disease to guide treatment. Their clinical value depends on whether the information they provide leads to improved patient outcomes. This can be assessed by randomized trials, which compare patient outcomes from the new diagnostic test versus the old test strategy. So, the current paper aims to focus on the practical utility of this rapidly emerging plethora of periodontal microbiological diagnostic tools, emphasizing the critical issues surrounding the clinical application of microbiologic investigations, employed for periodontal diagnosis.

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Role of Laboratory Tests in Enhancing Diagnosis and Treatment Planning for Dentists: A Review of Evidence-Based Practices

Albagieh,

Aldrees,

Alshamrani

et al. 2024

Cureus

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The purpose of this review is to simplify and guide dentists through the main laboratory investigations frequently used in dentistry for diagnosis and patient management. It emphasizes the critical role of laboratory tests in dental practice, highlighting their significance for accurate diagnosis, effective treatment planning, and ongoing monitoring of oral health. Systemic conditions often manifest through oral symptoms, making laboratory assessments essential for identifying undiagnosed health issues that may impact dental treatment outcomes. A comprehensive literature search was conducted using PubMed and Google Scholar to gather relevant studies, ensuring a thorough examination of existing knowledge on the subject. This review defines commonly used laboratory tests, including complete blood count (CBC), coagulation tests, hemoglobin A1c (HbA1c), liver function tests, immunological assays, and microbiological and virological evaluations. Each test provides valuable insights into patient health, aiding in the detection of conditions such as anemia, diabetes, and liver disease, which can complicate dental procedures. By adopting an evidence-based, personalized approach to patient care, dental professionals can enhance safety and treatment success. This article underscores the necessity of integrating laboratory assessments into routine dental practice, promoting a holistic understanding of patient health and improving overall treatment outcomes.

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Immunofluorescence in oral lesions

Cited by 3 publications

References 6 publications

Revisiting pemphigus vulgaris: A case report and review of literature

Revisiting pemphigus vulgaris: A case report and review of literature

Microbiological Aids in Periodontics

Role of Laboratory Tests in Enhancing Diagnosis and Treatment Planning for Dentists: A Review of Evidence-Based Practices

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