Immunogenicity of Ad26.COV2.S prime and two subsequent doses of mRNA SARS‐CoV‐2 vaccines in solid organ transplant recipients: A case series

Chang, Amy; Mitchell, Jonathan; Alejo, Jennifer L; Chiang, Teresa Po‐Yu; Abedon, Aura T; Kim, Jake D; Avery, Robin K.; Tobian, Aaron A.R.; Levan, Macey L; Warren, Daniel; Garonzik-Wang, Jacqueline M; Massie, Allan B.; Segev, Dorry L.; Werbel, William A

doi:10.1111/ctr.14772

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Vaccination Policies: History Present and Solutions History1

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2023

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“…The NIH also has a clinical trial underway to study if immune responses to vaccination improve when immunosuppression medication is temporarily reduced in the days leading up to and following vaccination (76,77). Though still unmatched to the general population, as boosters became available in the US, data shows that additional mRNA inoculations increase antibody titers for the majority of solid organ transplant patients (78,79).…”

Section: Vaccination Policies: History Present and Solutions Historymentioning

confidence: 99%

The impact of COVID-19 on kidney transplant care

Zhang

Kodali²,

Mour³

et al. 2023

Front. Med.

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The SARS-CoV-2 virus precipitated the coronavirus 2019 (COVID-19) pandemic, which placed considerable strain on healthcare systems and necessitated immediate and rapid alterations in the delivery of healthcare. In the transplant population, COVID-19 directly impacts an inherently vulnerable population in the setting of immunosuppression and co-morbidities, but also further complicates the clinical evaluation and management of kidney transplant candidates and recipients in a strained healthcare environment being challenged by the pandemic. Many transplant centers around the world saw mortality rate spikes in organ recipients related to COVID-19, and changes in care delivery abound. This review evaluates the care of the kidney transplant patient through all phases of the process including pre-operative evaluations, perioperative care, post-transplantation considerations, and how the global pandemic has changed the way we care for our patients.

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Section: Vaccination Policies: History Present and Solutions Historymentioning

confidence: 99%