Immunogenicity of COVID‐19 vaccines in patients with diverse health conditions: A comprehensive systematic review

Cho, Kyuyeon; Park, Seoyeon; Kim, Eun Young; Koyanagi, Ai; Jacob, Louis; Yon, Dong Keon; Lee, Seung Won; Kim, Min Seo; Raduà, Joaquim; Elena, Dragioti; Smıth, Lee

doi:10.1002/jmv.27828

Cited by 15 publications

(11 citation statements)

References 47 publications

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“…Dear Editor, During the epidemic of COVID-19 disease worldwide, applying COVID-19 vaccination can effectively protect humans from serious symptoms and help reduce long-term effects. 1 However, COVID-19 vaccines have been linked to some potential side effects. COVID-19 mRNA vaccine-associated dermatomyositis (DM) with the anti-TIF-1y-positive case was first reported in 2021.…”

mentioning

confidence: 99%

A case of Anti‐MDA5‐Positive dermatomyositis after inactivated COVID‐19 vaccine

Li-li

Liu

et al. 2022

Acad Dermatol Venereol

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confidence: 99%

A case of Anti‐MDA5‐Positive dermatomyositis after inactivated COVID‐19 vaccine

Li-li

Liu

et al. 2022

Acad Dermatol Venereol

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“…The average response rate of the survey over 15 years was 95.2% (Supporting Information: Table ). This anonymous self‐reporting online survey used proportional allocation sampling based on stratified, clustered, multi‐stage, and weight information to make a nationally representative sample of middle‐ and high‐school students 14,15 . To minimize the sampling error, the population was divided into 117 strata using 39 regional groups and school level as stratification variables 16…”

Section: Methodsmentioning

confidence: 99%

National trends in physical activity among adolescents in South Korea before and during the COVID‐19 pandemic, 2009−2021

Kwon

Koo

Lee

et al. 2023

Journal of Medical Virology

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With the ongoing COVID‐19 pandemic, several previous studies from different countries showed that physical activity (PA) decreased during the COVID‐19 outbreak. However, few studies have examined the recent tendency of PA in the adolescent population. Thus, we aimed to investigate the long‐term trend of PA in Korean youth and the prevalence changes between before and during the COVID‐19 pandemic. Data from Korea Youth Risk Behavior Web‐Based Survey (KYRBS) was collected for consecutive years between 2009 and 2021. The period was separated into prepandemic (2009−2019), early‐pandemic (2020), and mid‐pandemic (2021). Self‐reported amount of PA was categorized into four groups (insufficient, aerobic, muscle strengthening, and both physical activities) according to World Health Organization (WHO) PA guidelines. A total of 840 488 adolescents aged 12−18 who fully responded to the survey were selected (response rate: 95.2%). The 13‐year trends in the proportion of adolescents who reported aerobic and muscle‐strengthening activities met or exceeded 2020 WHO exercise guidelines for adolescents plateaued (11.9% from 2009 to 2011, 14.2% from 2018 to 2019, 14.4% from 2020, and 14.0% from 2021); however, the slope decreased during the pandemic (βdiff, −0.076; 95% confidence interval [CI], −0.123 to −0.029). Proportion of sufficient aerobic exercise among adolescents sharply decreased midst the pandemic (28.0% from 2009 to 2011, 29.4% from 2018 to 2019, and 23.8% from 2020; βdiff, −0.266; 95% CI, −0.306 to −0.226) but increased again in 2021 (26.0% from mid‐COVID 19; 95% CI, 25.4−26.7). Similar patterns were observed in Metabolic Equivalent Task (MET) score (MET‐min/week; 804.1 from 2018 to 2019, 720.9 from 2020, and 779.6 from 2021). The mean difference in MET score between pre‐COVID and post‐COVID was −55.4 MET‐min/week (95% CI, −70.5 to −40.3). Through a nationwide representative study, there was no significant difference with regard to the number of Korean adolescents who achieved the PA guidelines (pre and postpandemic); however, the prevalence of recommended levels of PA needs to increase more based on the trend before the COVID‐19 outbreak. The findings of this study suggest reinforcement of the importance of public health policies for Korean youths to be more physically active, especially during and after the pandemic.

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“…For this reason, the effectiveness of the COVID-19 vaccine was examined in patients with different clinical conditions. Consequently, its positive impact on their immune system was demonstrated [ 6 ]. Moreover, the clinical picture refers to a multisystemic symptomatology should be also present in long COVID [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Potential Anti-Inflammatory and Anti-Fatigue Effects of an Oral Food Supplement in Long COVID Patients

Noce,

Marrone,

Di Lauro

et al. 2024

Pharmaceuticals

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Long coronavirus disease (COVID) syndrome leads to chronic inflammatory state onset that can have a multisystem impact and compromise organ function. Moreover, long COVID syndrome is often characterized by the presence of chronic fatigue, which affects subjects’ daily activities and worsens their quality of life. The aim of our double-blind, placebo-controlled randomized trial (protocol code RS 150.21, approved on 4 November 2021) was to evaluate the beneficial effects of the consumption of 2 cps/day, for two months, of an oral food supplement (OFS), based on Echinacea angustifolia, rosehip, propolis, royal jelly and zinc, in long COVID patients, compared to a two-month placebo period. The OFS’s vitamin C content was equal to 22.17 mg/g (8.87 mg/capsule). The OFS’s total polyphenol content was 43.98 mg/g gallic acid equivalents. At the end of the in vivo study, we highlighted a significant decrease in the inflammatory parameters in the OFS period, compared to the placebo period (neutrophil-to-lymphocyte ratio, p = 0.0455; monocyte to-lymphocyte ratio, p = 0.0005; C-reactive protein, p = 0.0145). Our study also highlighted a significant increase in vitamin D serum values (p = 0.0005) and, at the same time, an improvement in patients’ life quality and a reduction in fatigue, monitored by the fatigue severity scale. This study showed the OFS’s beneficial effects on the inflammatory state, fatigue and quality of life in long COVID patients.

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Immunogenicity of COVID‐19 vaccines in patients with diverse health conditions: A comprehensive systematic review

Cited by 15 publications

References 47 publications

A case of Anti‐MDA5‐Positive dermatomyositis after inactivated COVID‐19 vaccine

A case of Anti‐MDA5‐Positive dermatomyositis after inactivated COVID‐19 vaccine

National trends in physical activity among adolescents in South Korea before and during the COVID‐19 pandemic, 2009−2021

Potential Anti-Inflammatory and Anti-Fatigue Effects of an Oral Food Supplement in Long COVID Patients

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