Immunoglobulin G absorption from pooled maternal colostrum, commercial powder and freeze-dried colostrum by newborn calves

Abstract

-For many reasons, a lot of newborn ruminants have no access to their mother's colostrum and are therefore not protected against neonatal diseases. Many commercial colostra-replacers are now available, but their ability to pass the intestinal wall is not well established. Therefore, two experiments were carried out to test the value of two maternal colostra, freeze-dried immunoglobulins extracted from the colostra of Holstein cows, and a commercial dried colostrum powder, as colostrum substitute. Fifty-seven Holstein calves were fed the same immunoglobulin concentration exactly 1, 7 and 15 h after birth. They were divided into four groups A, B, C and D with respectively 16, 16, 13 and 12 animals. Total immunoglobulin G concentrations were the highest at 24 h in all groups but the freeze-dried colostrum was best absorbed. The IgG of the whole and the freeze-dried colostra were well absorbed by the calves: the second meal increased the IgG of the calves over 10 g . L -1 , usually considered as the minimum level of protection of the newborn. The commercial dried colostrum powder was not well absorbed and showed low immunoglobulin levels at 24 h postpartum. It was concluded that even when colostra are given in the same concentrations to calves, the absorption of immunoglobulins differ, because of the complexity and the probable sensitivity and alteration of colostrum components during technological treatments.birth / calf / colostrum / absorption / immunoglobulin G Résumé -Absorption des immunoglobines G chez le veau nouveau-né. Pour diverses raisons, de nombreux ruminants nouveau-nés n'ont pas accès au colostrum de leur mère pour se protéger contre les infections néonatales. Des substituts du colostrum sont actuellement disponibles sur le marché mais leur absorption intestinale par le nouveau-né n'est pas clairement établie. Deux A. N'Diaye Wereme et al. 316

The Effects of Colostrum Immunoglobulin on Strongyloides Infection in Mice

“…This positive respons of IgG compared to other controls group was associated with the function of colostrum antibodies which are thought to coat the mucosal surfaces lining the gut and prevent invasion by pathogenic organisms (Hurley and Theil, 2011). In addition, the supply of colostrum IgG from other parent as passive transport of antibodies serves to overcome the problems of microbial pathogenic and parasitic infections (Werem et al, 2001). This response has a similar impact as reported by Poulsen et al, (2010) that ingestion and absorption of the immunologic substances in colostrum by neonatal could reduce morbidity and mortality rates and have a positive influence on the future productivity.…”

Bovine Colostrum Silage: Physicochemical and Microbiological Characteristics at Different Fermentation Times

“…It is important to note that the physicochemical composition of BC differs according to the breed of animal and over the days in which it is excreted (Marnila and Korhonen, 2011;Morrill et al, 2012). For many reasons, many newborn ruminants do not have access to their mothers' colostrum immediately after birth: multiple births, acute mastitis, maladaptive maternal behavior mainly at first birth, etc., (Wereme et al, 2001). Therefore, it is necessary to create a colostrum bank for newborn calves that cannot be fed by their own mothers immediately after birth and for the preparation of immune colostrum products that can be used as food supplements or colostrum substitutes to provide effective protection against different enteric diseases in calves and humans (Alexieva et al, 2004).…”

Evaluation of homeopathic treatments in early lactation in buffalo cows and neonatal mortality in buffalo calf

“…This rapid closing of intestine reduces the incidence of infections in the calves [7]. Hence the need for early and proper administration of colostrums to the calves, as its failure or delayed recruitment or its poor quality predisposes the animals to neonatal infections [8,9]. Moreover, poor hygiene, the incorrect diet as well as lack or inadequate intake of colostrums, are the most important factors that promote the onset of diseases, as reported by Galiero (2001) [10].…”