Immunoglobulin G4–Related Disease Involving the Nasal Septum and Trachea

Ji, Yongjin; Liu, Rong; Zhao, Changqing

doi:10.1097/rhu.0000000000001257

Cited by 2 publications

(5 citation statements)

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“…This is a reported case of immunoglobulin G4-related disease (IgG4-RD) involving the nasal septum and trachea, which was, here, successfully managed with glucocorticoids. 1 Yes, we agree with Akiyama's position that our case is IgG4-related midline destructive disease, which is also called midline destructive lesion (MDL) in most works. [2][3][4] Midline destructive lesion is a clinical entity of unknown origin with nonspecific histopathological features.…”

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confidence: 80%

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Response to “IgG4-Related Midline Destructive Disease” by Akiyama M

Liu

Zhao

2020

J Clin Rheumatol

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W e wish to thank Prof. Akiyama for his comments. This is a reported case of immunoglobulin G4-related disease (IgG4-RD) involving the nasal septum and trachea, which was, here, successfully managed with glucocorticoids. 1 Yes, we agree with Akiyama's position that our case is IgG4-related midline destructive disease, which is also called midline destructive lesion (MDL) in most works. [2][3][4] Midline destructive lesion is a clinical entity of unknown origin with nonspecific histopathological features. It is characterized by ulceration and progressive destruction of the nose, paranasal sinuses, and palate. 4 As Akiyama stated in the letter, although the etiologies of MDL are related to specific known diseases, some conditions of MDL still remain unexplained and are therefore labeled "idiopathic." Recently, a series of cases presenting as MDL and attributed to IgG4-RD have greatly expanded the spectrum of IgG4-RD manifestations. [4][5][6][7] It is essential to distinguish this entity from other conditions known to cause MDL because they require different approaches to treatment and management.We appreciate Akiyama's description of the correlation between antineutrophil cytoplasmic antibody-associated vasculitis (ANCA-associated vasculitis) and IgG4-RD. Antineutrophil cytoplasmic antibody-associated vasculitis includes granulomatosis with polyangiitis (GPA),

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supporting

confidence: 80%

“…We wish to thank Prof. Akiyama for his comments. This is a reported case of immunoglobulin G4–related disease (IgG4-RD) involving the nasal septum and trachea, which was, here, successfully managed with glucocorticoids 1 …”

mentioning

confidence: 83%

Response to “IgG4-Related Midline Destructive Disease” by Akiyama M

Liu

Zhao

2020

J Clin Rheumatol

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“…They reported the case of so-called immunoglobulin G4 (IgG4)-related midline destructive disease. 1 Immunoglobulin G4-related disease is a chronic fibroinflammatory disease characterized by serum IgG4 elevation and IgG4-positive plasma cell infiltration. 2 Typical clinical manifestations are autoimmune pancreatitis and Mikulicz disease, but this disease entity can affect every single organ as a tumefactive or hypertrophic lesion.…”

Section: Immunoglobulin G4-related Midline Destructive Diseasementioning

confidence: 99%

“…I read with great interest the article by Ji et al 1 published in your journal. They reported the case of so-called immunoglobulin G4 (IgG4)–related midline destructive disease 1 .…”

mentioning

confidence: 99%