IMMUNOGLOBULIN (IgG, IgA and IgM) LEVELS IN PRIMARY CARCINOMA OF THE LIVER AND CIRRHOSIS OF THE LIVER IN SINGAPORE

Chew, B. K.; Yu, Moses; Wee, Richard

doi:10.5694/j.1326-5377.1970.tb84671.x

Cited by 3 publications

(2 citation statements)

References 7 publications

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“…The level of IgE has relation with hepatitis B surface antigen. 31,6 Hepatocellular carcinoma is reflecting the fifth most common cancer and sorted the second most common cause of death world widely. 5 In Egypt, it represents the fourth common cancer.…”

Section: Introductionmentioning

confidence: 99%

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Serum total IgE as immunological marker in patients with chronic hepatitis B Virus infection, and hepatitis B related hepatocellular carcinoma

Khalil

Eldin

Sadek

et al. 2023

EJI

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This study evaluated the efficacy of IgE in predicting disease progression in chronic hepatitis B virus (HBV) and HBV related hepatocellular carcinoma (HCC) compared to normal controls. The study included 60 HBV-infected patients. Of these, 30 patients with chronic hepatitis B but not related to HCC and 30 patients with related HCC. Serum level of IgE was measured by ELISA. Serum level of IgE was higher in HCC patients than non-HCC patients (p< 0.005). Significant correlations were detected between IgE, transaminases (ALT, AST), alpha-fetoprotein and severity scores in chronic hepatitis B (CHB) patients. The level of IgE was correlated with HB viral load. Stronger correlations were evident between IgE, prothrombin time and total bilirubin. In conclusion, IgE levels may be considered as non-invasive markers for monitoring liver disease progression in CHB.

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Section: Introductionmentioning

confidence: 99%

“…Some studies demonstrated the role of immunoglobulins G and M in chronic hepatitis B infection. 29,31 This study aimed to determine whether IgE antibodies have a role in predicting disease progression in HBV and HBV related HCC.…”

Section: Introductionmentioning

confidence: 99%