Immunoglobuttn Administration into Cerebral Subarachnoid Space in a Child with Hypogammaglobulinemia and Aseptic Meningoencephalitis

A 53-year-old female was diagnosed acute type adult T cell lymphoma (ATL). After anti-CCR4 antibody mogamulizmab administration, we performed non-myeloablative cord-blood transplantation. On day 22, GVHD appeared after engraftment. After beginning of PSL, cytomegaloviral (CMV) meningo-encephalitis was occurred. Since the anti-viral drugs were not effective enough, we treated her with intrathecal administration of non-complete human immunoglobulin, which transiently improved her level of consciousness and decreased the CMV viral load. But she died of the refractory CMV encephalitis. Further examination is necessary about intrathecal administration of non-complete human immunoglobulin therapy.

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Immunoglobuttn Administration into Cerebral Subarachnoid Space in a Child with Hypogammaglobulinemia and Aseptic Meningoencephalitis

Cited by 2 publications

References 6 publications

Combined Treatment of pH4 Treated Acidic Human Normal Immunoglobulin and Antibiotics for Severe Infections in Neurosurgical Patients

Combined Treatment of pH4 Treated Acidic Human Normal Immunoglobulin and Antibiotics for Severe Infections in Neurosurgical Patients

Efficacy and ploblem of non-complete human immunoglobulin therapy for refractory cytomegaloviral meningo-encephalitis after hematopoietic stem cell transplantation

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