Immunohistochemical assessment of CuZn-superoxide dismutase in the human genital organs.

Toxic effects of alcohol intake on prostate of rats

“…Excess generation of these species in vivo results in lipid peroxidation [19]. We observed that chronic ethanol intake increased lipoperoxide production (Table II), and some studies have shown that sexual dysfunction induced by ethanol results from lipid peroxidation [20]. Holland et al [21] reported that superoxide (O 2 − ) and not H 2 O 2 was the oxygen-reactive species for lipoperoxide formation and testicular damage after alcohol intake, since even though O 2 − is decreasing, it gives rise to lipid peroxidation.…”