Immunohistochemical Coexpression of VEGF and CD34 in Ameloblastoma

Abstract

Background:Angiogenic potential m most tumors; characterized by VEGF and vascular bed density around tumor islands, is believed to be an important marker in predicting tumor growth, recurrence and metastasis. Materials and Methods:The study included 50 cases of ameloblastomas. From each case 4 μm sections were stained IHC with antivascular endothelial growth factor antibody-and endothelial lined vessels anti CD34 antibody to evaluate their expression and intensity in relation to their clinicopathological features.