Immunohistochemical evaluation of vascular neoplasms

Swanson, Paul E.; Wick, Mark R.

doi:10.1016/0738-081x(91)90014-c

Cited by 17 publications

(1 citation statement)

References 80 publications

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“…Factor VIII‐related antigen, one of the three components of coagulation factor VIII, has been used as a marker for vascular endothelial cells 31 , 32 . However, negative staining of neoplastic endothelial cells for factor VIII‐related antigen is not uncommon and probably results chiefly from loss of the antigen by neoplastic cells 33 , 34 . In our cases, factor VIII‐related antigen proved to be an unreliable marker for neoplastic endothelial cells of CA.…”

Section: Discussionmentioning

confidence: 99%

Verrucous angiosarcoma of the skin: a distinct variant of cutaneous angiosarcoma

et al. 1998

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Verrucous epidermal changes seem to be a manifestation of pseudocarcinomatous hyperplasia, presumably caused by lymphoedema and the superficial setting of the tumour in the papillary dermis. It is important to be aware of this presentation of angiosarcoma because verrucous epidermal changes may be seen in a wide variety of skin diseases. Furthermore, a biopsy that includes the dermis is necessary to ensure that the angiosarcoma underlying the hyperplastic epidermis is correctly identified. The descriptive appellation verrucous angiosarcoma of the skin is proposed to designate a newly recognized variant of angiosarcoma.

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Section: Discussionmentioning

confidence: 99%