Immunohistochemical expression of epidermal growth factor receptor in breast cancer

Nozoe, Tetsuo; Mori, Emiko; Iguchi, Tomohiro; Egashira, Akinori; Adachi, Eisuke; Matsukuma, Akito; Ezaki, Takahiro

doi:10.1007/s12282-010-0200-2

Cited by 7 publications

(3 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Based on well known knowledge that pathological nuclear grade (NG) has been considered to show a cellular proliferation potential of breast cancer (18) in addition to the incidence of TNBC with more aggressive potential of breast cancer (19,20), we recently suggested a cumulative scoring system (TGS) as a newly devised criteria to predict tumor recurrence and outcome of the patients with IDC by combination of NC and the incidence of TNBC with the results that TGS could classify prognosis and time to progression of the patients with breast IDC with a preferable stratification (4).…”

Section: Discussionmentioning

confidence: 99%

Further evidence to demonstrate the significance of serum appearance of anti-p53 antibody as a marker for progressive potential in invasive ductal carcinoma of the breast

Nozoe

Kono

et al. 2017

J. Med. Invest.

Self Cite

View full text Add to dashboard Cite

: Background : Serum appearance of anti-p53 antibody (p53Ab) has been reported as an indicator for progressive potential of human tumor tumors including breast cancer. But its significance in breast cancer has not been discussed fully. Methods : Relationship between serum appearance of p53Abs and representative data accounting for progressive potential in breast cancer, nuclear grade (NG), triple negative cancer, and the cumulative score based on these two data (TGS) was investigated among 129 women with invasive ductal carcinoma (IDC) of the breast, who had been treated with surgical resection. Results : There was a significant correlation between appearance of p53Abs and recurrence of the tumors (P = 0.035). Significant correlation of serum appearance of p53Abs with negative expression of ER (P = 0.011), the proportion of TNBC (P = 0.013), NG (P = 0.017), and TGS (P = 0.0005). Conclusions : Preoperative serum appearance of p53Abs can be correlated with pathological nuclear grade, incidence of triple negative breast cancer, and TGS. These results might demonstrate more powerful significance of serum appearance of p53Abs as an indicator of progressive potential in IDC of the breast.

show abstract

Section: Discussionmentioning

confidence: 99%

Further evidence to demonstrate the significance of serum appearance of anti-p53 antibody as a marker for progressive potential in invasive ductal carcinoma of the breast

Nozoe

Kono

et al. 2017

J. Med. Invest.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Moreover, the proportion of tumor recurrence in the abdominal organs including the gastrointestinal tract, ovary and peritoneum has been revealed to be higher in patients who have invasive lobular carcinoma (6,7), and it is well known that tumor recurrence is much more frequent in cases of triple negative breast cancer (8). Therefore, a meticulous follow-up may be mandatory.…”

Section: Discussionmentioning

confidence: 99%

Unilateral multicentric cancer of the breast containing two different histopathological types: Case report

Nozoe¹,

Sueishi

Mori

et al. 2012

Oncology Letters

Self Cite

View full text Add to dashboard Cite

Abstract. Unilateral multicentric cancer of the breast containing a tumor with a specific histopathological type is comparatively rare. We, herein, report a case of an unilateral multicentric cancer of the breast containing two separate tumors diagnosed as a papillo-tubular carcinoma and an invasive lobular carcinoma. In addition to the difference in histological type, these two tumors also had different patterns of expression of hormonal receptors reflecting the cellular aggressiveness. Therfore, these tumors may be formed through multicentric tumorigenesis.

show abstract

“…TNBC accounts for the subgroup of breast cancer associated with aggressive behavior of the tumor and therefore the unfavorable prognosis of the patients [24], for which the definitive therapeutic strategies remain controversial [25]. Therefore the genetic features of TNBC have been investigated by using molecular and biological methodologies in order to identify the patients who would be treated with suitable therapeutic options [26].…”

Section: Discussionmentioning

confidence: 99%

Serum appearance of anti-p53 antibody in triple negative breast cancer

et al. 2010

Self Cite

View full text Add to dashboard Cite

show abstract

Immunohistochemical expression of epidermal growth factor receptor in breast cancer

Abstract: Knowledge of a patient's immunohistochemical EGFR expression, which could be one of the key molecular findings related to molecular-targeting therapy, might be useful information to treat triple-negative breast cancer.

Cited by 7 publications

References 21 publications

Further evidence to demonstrate the significance of serum appearance of anti-p53 antibody as a marker for progressive potential in invasive ductal carcinoma of the breast

Further evidence to demonstrate the significance of serum appearance of anti-p53 antibody as a marker for progressive potential in invasive ductal carcinoma of the breast

Unilateral multicentric cancer of the breast containing two different histopathological types: Case report

Serum appearance of anti-p53 antibody in triple negative breast cancer

Contact Info

Product

Resources

About