“…To give an overview of significant loci obtained through GWAS, we summarized these reported significant variants in the Supplementary Table S10 . Among the 14 identified genes, TPM2 , HOXB2 , and MGMT have been shown to be associated with EM in a few previous studies [37] , [38] , [39] . Specifically, TPM2 encodes beta-tropomyosin, which plays a role in muscle contraction and motility, and helps maintain cell shape and cell-matrix interactions.…”