2024
DOI: 10.1101/2024.10.30.621047
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Immunologic comparisons of strain and induction method in an improved mouse model of intrauterine fibrosis

Jamie L. Hernandez,
Jonathan Daniel,
Jessica L. Stelzel
et al.

Abstract: Intrauterine adhesions are growths of fibrotic tissue within the uterine cavity and can arise from a variety of tissue-damaging stimuli. Immune cells are known to mediate fibrotic responses, but specific mechanisms require further elucidation. Here, we compared intrauterine fibrosis development and immune responses across different mouse strains and induction methods. We aimed to identify a consistent and more clinically relevant mouse model of intrauterine fibrosis, whether immune responses differ in response… Show more

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