Immunologic Response to Bacterial Vaccine

Eisen, A.H.; Bacal, H.L.

doi:10.1159/000229851

Cited by 8 publications

(3 citation statements)

References 7 publications

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“…Many consider that intrinsic asthma is largely due to allergic reactions to antigens in bacteria and viruses, and the many cases of asthma that are precipitated or aggravated by respiratory infections are said to support this view. Such cases may be caused by non-specific, non-allergic mechanisms (Blatt, 1961;Eisen and Bacal, 1967;Feingold, 1959). Respiratory infections may induce an increased hyperreactivity by non-immunological mechanisms.…”

Section: Intrinsic Asthma: An Exclusion Diagnosismentioning

confidence: 99%

Allergic asthma in childhood.

K¹

1969

Archives of Disease in Childhood

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Section: Intrinsic Asthma: An Exclusion Diagnosismentioning

confidence: 99%

Allergic asthma in childhood.

K¹

1969

Archives of Disease in Childhood

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“…The evidence for the presence of infection in asthma is mainly based on clinical findings of fever, leucocytosis and sometimes patchy consolidation in the lungs. Most descriptions of ihe treatment of asthma include detail on the antibiotic recommended (Eisen, 1969). The microbiological evidence for infection is small and mainly concerned with bacterial allergy, which has protagonists (Eisen & Bacal, 1967;Hampton, Johnson & Galaktos, 1963;Crump, 1954) and disbelievers (Aas et al, 1963;Fontana ('/ al., 1965).…”

Section: Discussionmentioning

confidence: 99%

“…However, many patients, particularly children with a history suggesting that an upper respiratory tract infection has led to an attack of asthma, are treated with antibiotics. Rapid recovery from the attacks is ascribed to chemotherapy (Eisen. 1969).…”

Section: Introductionmentioning

confidence: 99%

The role of infection in the morbidity of asthmatic children admitted to hospital

Disney

Matthews

Williams

1971

Clin Experimental Allergy

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Summary Two aspects of the role of infection in asthmatic attacks in children have been investigated. Virus isolations from children admitted to a paediatric department during 1968 showed close correlation with the incidence of admissions with upper respiratory tract infection and with lower respiratory tract infection. The peaks of virus isolation corresponded to the peaks of respiratory infection admissions. There was a clear dissociation between virus isolations and admissions with acute asthma. Fifty‐one children admitted with clinical acute attacks of asthma were investigated more thoroughly. Only three viruses were isolated from these case? compared to eleven viruses isolated from a control group of children with respiratory infections. The incidence of bacterial pathogens was similar in both groups. Serological evidence of virus infection was obtained in two out of twenty‐six children with asthma and in four out often children with respiratory infections. Our results indicate that bacterial or viral infections are not responsible for the autumn peak of asthma admissions.

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