1988
DOI: 10.1016/s0013-9351(88)80024-0
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Immunological and respiratory findings in spice-factory workers

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Cited by 42 publications
(22 citation statements)
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References 31 publications
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“…Reseptörlerin aktivasyonu ile salınan substance-P, neurokinin-A, neurokinin-P, kalsitonin gen ilişkili peptid gibi nö-ropeptidlerin aktivasyonu ile mukus sekresyonunu artırır, bronkokonstriksiyon ve nörojenik inflamasyon meydana gelir (2). Bu peptidlerin kapiller endoteline lökosit göçünü artırarak, özelikle tekrarlayan maruziyetlerde hava yollarında kalıcı inflamasyona yol açtıkları düşünülmektedir (3,4). Akut inhalasyon hasarında, irritan ajanın solubilitesi, aerodinamik özellikleri, pH ve konsantrasyonuna bağlı olarak etkilenen alan ve derecesi belirlenir.…”
Section: Discussionunclassified
“…Reseptörlerin aktivasyonu ile salınan substance-P, neurokinin-A, neurokinin-P, kalsitonin gen ilişkili peptid gibi nö-ropeptidlerin aktivasyonu ile mukus sekresyonunu artırır, bronkokonstriksiyon ve nörojenik inflamasyon meydana gelir (2). Bu peptidlerin kapiller endoteline lökosit göçünü artırarak, özelikle tekrarlayan maruziyetlerde hava yollarında kalıcı inflamasyona yol açtıkları düşünülmektedir (3,4). Akut inhalasyon hasarında, irritan ajanın solubilitesi, aerodinamik özellikleri, pH ve konsantrasyonuna bağlı olarak etkilenen alan ve derecesi belirlenir.…”
Section: Discussionunclassified
“…Allergic contact dermatitis and urticaria (hives) have been reported in response to skin exposure to certain spices [Zuskin et al 1988a]. Occupational asthma has been linked to exposure to a range of spices, including cinnamon, paprika, mace, coriander, aniseed, garlic, and onion [Sastre et al 1996;van der Walt et al 2010van der Walt et al , 2013.…”
Section: Confidential Medical Interviewsmentioning
confidence: 99%
“…In a study of 45 spice factory workers in Yugoslavia (matched with an unexposed comparison group of workers of the same sex, age, and smoking status), intradermal skin prick testing with mixed spice dust allergen showed positive skin reactions in 73% of the exposed workers and 33% of the unexposed workers [Zuskin et al 1988a]. The study showed a statistically significant difference for allergic skin reactions (skin prick testing), chronic respiratory symptoms, and increased immunoglobulin E serum levels of spice dust antigens between the factory workers and unexposed workers.…”
Section: Summary Of Workplace Exposures To Spice Dustmentioning
confidence: 99%
“…Allergy to some seasonings (paprika, coriander, mace, garlic, onion, and chili pepper) has been associated with occupational asthma [Sastre et al 1996;Añibarro et al 1997;van der Walt et al 2010]. In spice factory workers, immune response to spice dust was common (73%) and associated with respiratory symptoms of cough, chest tightness, and throat irritation [Zuskin et al 1988].…”
Section: Flavorings (Alpha-diketones)mentioning
confidence: 99%