Immunomodulation in Viral Infections: Virus or Infection-Induced?

Group B coxsackieviruses readily establish persistent infections in human lymphoid cell lines

“…The interactions group B coxsackieviruses (CVB) establish with immunocompetent cells are little understood. The problem is of interest because CVB are important human pathogens, and virus-immunocyte interplay can influence many aspects of infection and disease (3). CVB-infected mice are immunosuppressed (4) and present a generalized depletion of lymphoid organs (18).…”