Immunomodulators

Enshasy, Hesham El

doi:10.1007/978-3-642-11458-8_8

Cited by 6 publications

(9 citation statements)

References 223 publications

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“…Some of these compounds exhibiting also anticancer activities were isolated from different types of macrofungi [8, 33]. Different types of BRM were applied as immunotherapeutic agents and showed significant activity as potent anticancer compounds in both in vitro and in vivo models [34–36].…”

Section: Functional Chemical Compounds Of Health Valuementioning

confidence: 99%

“…Whereas, based on the symbiotic behavior of truffles as typical ectomycorrhiza, they were cultivated in soil with their host plant in truffle green houses in semiarid area [ 6 , 7 ]. With the rapid growth of bioprocess technology industries, it was possible to cultivate many macrofungi in submerged culture under fully controlled conditions to produce the desired biotherapeutic compounds in high concentrations, in shorter production time, and under fully sterile conditions according to cGMP [ 8 – 10 ].…”

Section: Introductionmentioning

confidence: 99%

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Mushrooms and Truffles: Historical Biofactories for Complementary Medicine in Africa and in the Middle East

El‐Enshasy

Elsayed

Aziz

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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The ethnopharmaceutical approach is important for the discovery and development of natural product research and requires a deep understanding not only of biometabolites discovery and profiling but also of cultural and social science. For millennia, epigeous macrofungi (mushrooms) and hypogeous macrofungi (truffles) were considered as precious food in many cultures based on their high nutritional value and characterized pleasant aroma. In African and Middle Eastern cultures, macrofungi have long history as high nutritional food and were widely applied in folk medicine. The purpose of this review is to summarize the available information related to the nutritional and medicinal value of African and Middle Eastern macrofungi and to highlight their application in complementary folk medicine in this part of the world.

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Section: Functional Chemical Compounds Of Health Valuementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Mushrooms and Truffles: Historical Biofactories for Complementary Medicine in Africa and in the Middle East

El‐Enshasy

Elsayed

Aziz

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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“…The anticancer activity of β-glucans chiefly applies to forms (1→3)/(1→6)-β. The antineoplastic properties of β-glucans in mushrooms result from strong intensification of the immune response rather than from their direct cytotoxic properties [46,47]. β-glucans in mushrooms also exhibit antibacterial, antiviral and anti-allergic properties.…”

Section: Specific Polysaccharidesmentioning

confidence: 99%

Nutritional value and health-promoting properties of Agaricus bisporus (Lange) Imbach

et al. 2018

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Summary The white button mushroom Agaricus bisporus (Lange) Imbach is an edible mushroom of top economic significance. In recent years the consumption of fruiting bodies of this species has been increasing in Poland. The article characterises the chemical composition and health-promoting properties of white button mushrooms. The latest scientific research confirms that the fruiting bodies of white button mushroom have high nutritional value. They contain good quality proteins, necessary unsaturated fatty acids, fibre, some vitamins and numerous minerals. Apart from that, white button mushroom fruiting bodies contain a wide range of bioactive substances, which have a positive influence on health, such as polysaccharides, glyco-proteins, tocopherols, polyphenols and other antioxidants, e.g. ergothioneine. Apart from the antioxidant properties, the white button mushroom also has anti-inflammatory, antimicrobial, antifungal, anticancer, immunomodulatory, hepatoprotective and anti-atherosclerotic activities.

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“…For example, mushrooms are traditionally consumed in many Asian countries as healthy food to prevent diseases and stimulate immune system. Mushrooms are rich source of different types of bioactive polysaccharides and many other low molecular weight compounds of immunomodulator, antioxidant, antimicrobial and anticancer activities [96]. However, antibiotic discovery in early 1940s was the most important event in the history of therapeutics microbial metabolities application in human health.…”

Section: Microbial Cells and Human Wellnessmentioning

confidence: 99%

Biotechnology for Wellness Industry: Concepts and Biofactories

Sarmidi¹,

Enshasy²

2012

Int J Biotech Well Ind

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One of the major issues in the 21 st. century facing humankind is on how to stay healthy and delay the onset of chronic metabolic diseases. Chronic metabolic chronic diseases still afflict a substantial percentage of modern human population despite the advances in medical and health care technologies. They create a long-term financial burden to the nation as well as reducing the productivity and the quality of life. In the recent years, the wellness approach to healthy living by mean of health enhancement and disease prevention has been increasing in popularity. There is a tremendous global and local interest for wellness products. Wellness sector focuses on providing products and services to a wider community to improve appearance, slow down the effect of ageing and to reduce the risk of developing chronic metabolic diseases. The wellness products are intended for the promotion of health in soil, plants, animals and human. Soil health is the foundation of wellness as healthy and productive soil produce healthy plants and crops in turn produced healthy animals for human nutrition. It is a fact that human health is closely associated with the practice of healthy life style that include consuming wholesome nutrients, living in a non-toxic environment and enhancing physical and mental fitness. These factors in turn promote the attainment and maintenance of cellular homeostasis. Under cellular homeostasis the cellular metabolic activities are at their optimum. In this regard traditional and modern biotechnology offer comprehensive list of natural ingredients and metabolites essential for cellular metabolism. These natural ingredients and metabolites are derived from microbial, algal, plant, animals, and human sources. Most of these natural products are increasingly made available by using innovative bioprocess technologies as more of them are main components of functional foods, nutraceuticals, cosmeceuticals and therapeutics. Bioprocess industries are considered as source for both health and wealth. The new concept of bioprocess industries is based on using different types of cells as small micro-bio-factories. These small biofactories belong to different classes of living organisms ranging from the most primitive prokaryotic bacterial cells up to high eukaryotic human cells. In the present review, the concept of bioprocess design and cultivation of cells up to the industrial level will be presented.

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Immunomodulators

Cited by 6 publications

References 223 publications

Mushrooms and Truffles: Historical Biofactories for Complementary Medicine in Africa and in the Middle East

Mushrooms and Truffles: Historical Biofactories for Complementary Medicine in Africa and in the Middle East

Nutritional value and health-promoting properties of Agaricus bisporus (Lange) Imbach

Biotechnology for Wellness Industry: Concepts and Biofactories

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