Immunomodulatory and ameliorative effects of Lactobacillus and Saccharomyces based probiotics on pathological effects of eimeriasis in broilers

Awais, Mian Muhammad; Jamal, Muhammad; Akhtar, Masood; Hameed, Muhammad Raza; Anwar, Muhammad İrfan; Ullah, Muhammad Irfan

doi:10.1016/j.micpath.2018.10.038

Cited by 29 publications

(38 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, the ratio of Lactobacilli to Escherichia coli in the ileum and caecum contents was increased by dietary S. cerevisiae and its superfine powders (Zhu et al 2017). Finally, third possible reason for the positive effects of S. cerevisiae and L. acidophilus to improves microbial balance could be linked to their immunostimulatory effects that have been reported in different animal models (Koenen et al 2004;Li et al 2005;Ashraf and Shah 2014;Awais et al 2019).…”

Section: Microorganism Enumeration and Ph Measurementsmentioning

confidence: 94%

Effects of microbial fermented sesame meal and enzyme supplementation on the intestinal morphology, microbiota, pH, tibia bone and blood parameters of broiler chicks

Hajimohammadi

Mottaghitalab

Hashemi

2020

Italian Journal of Animal Science

View full text Add to dashboard Cite

This study was conducted to compare the broiler chicks responses to raw sesame meal (RSM), either processed by microbial fermentation or enzyme supplementation. A total of 420-day-old boiler chicks (Ross 308V R ) were allocated to a completely randomised design experiment with 7 treatments and 5 replicates (12chicks/replicate). Treatments include: basal diet based on soybean meal (SBM), SBM substitution with 15 and 25% RSM either with phytase [5000 FTU phyzyme XP/g (PHX)] (RSM 15 þ PHX, and RSM 25 þ PHX) or without enzyme (RSM 15 , RSM 25 ), and two diets in which SBM substituted with 15 and 25% fermented sesame meal (FSM 15 and FSM 25 ). The results indicated that fermentation process decreased oxalate and phytic acid (51% and 44%, respectively), and simultaneously increased in crude protein (13%), ether extract (11%) and available phosphorus (61%) (p < .05). Moreover, compared to SBM and RSM treatments, broilers fed diets containing FSM, lead to significant (p < .05) increase in Lactobacillus and decrease in coliforms count in the ileum. Furthermore, the broilers fed FSM 15 diet had the lowest reduction in Escherichia coli population in the crop (p < .05). In the jejunum, the highest villus height was observed in the FSM 25 diet compared to RSM diets (p < .05). Compared to SBM, inclusion of FSM 25 to broiler rations resulted in blood triglycerides and cholesterol reduction by 30.7 and 23.7%, respectively (p < .05). Conclusion is that fermentation process can improve nutrient value of the RSM and could be considered as a protein source in broilers diet. HIGHLIGHTS:Fermentation process increased nutrient value of the sesame meal. Fermented sesame meal shifted intestinal microbial population more towards benefit bacteria. Fermented sesame meal increased the villus height in the jejunum and decreased blood triglycerides and cholesterol in broilers. ARTICLE HISTORY

show abstract

Section: Microorganism Enumeration and Ph Measurementsmentioning

confidence: 94%

Effects of microbial fermented sesame meal and enzyme supplementation on the intestinal morphology, microbiota, pH, tibia bone and blood parameters of broiler chicks

Hajimohammadi

Mottaghitalab

Hashemi

2020

Italian Journal of Animal Science

View full text Add to dashboard Cite

show abstract

“…Recombinant L. plantarum NC8 (containing Eimeria tenella protein) induced a higher percentage of a T-cell subset (CD3 + , CD4 + , and CD8 + ) and antibody levels, provided protection against E. tenella infection in chickens, and reduced lesion, cecum damage, and oocyst shedding (270). L. salivarius, L. johnsonii, and S. cerevisiae provided protection against Eimeria infection in chickens; reduced oocyst count, improved weight gain and FCR, and stimulated the immune response with higher antibodies (IgM and IgG) titer and lymphoproliferative response (271). Pender et al revealed that chickens receiving supplementation of commercially available probiotics; Primalac W/S (L. acidophilus, L. casei, E. faecium, and B. bifidium) showed lower mortality, higher body weight, and fewer Eimeria maxima-, Eimeria tenella-, and Eimeria acervulina-induced lesions; however, there was no effect on the immune response (272).…”

Section: Probiotics and Parasitic Diseasesmentioning

confidence: 99%

Modulatory Effects of Probiotics During Pathogenic Infections With Emphasis on Immune Regulation

et al. 2021

View full text Add to dashboard Cite

In order to inhibit pathogenic complications and to enhance animal and poultry growth, antibiotics have been extensively used for many years. Antibiotics applications not only affect target pathogens but also intestinal beneficially microbes, inducing long-lasting changes in intestinal microbiota associated with diseases. The application of antibiotics also has many other side effects like, intestinal barrier dysfunction, antibiotics residues in foodstuffs, nephropathy, allergy, bone marrow toxicity, mutagenicity, reproductive disorders, hepatotoxicity carcinogenicity, and antibiotic-resistant bacteria, which greatly compromise the efficacy of antibiotics. Thus, the development of new antibiotics is necessary, while the search for antibiotic alternatives continues. Probiotics are considered the ideal antibiotic substitute; in recent years, probiotic research concerning their application during pathogenic infections in humans, aquaculture, poultry, and livestock industry, with emphasis on modulating the immune system of the host, has been attracting considerable interest. Hence, the adverse effects of antibiotics and remedial effects of probiotics during infectious diseases have become central points of focus among researchers. Probiotics are live microorganisms, and when given in adequate quantities, confer good health effects to the host through different mechanisms. Among them, the regulation of host immune response during pathogenic infections is one of the most important mechanisms. A number of studies have investigated different aspects of probiotics. In this review, we mainly summarize recent discoveries and discuss two important aspects: (1) the application of probiotics during pathogenic infections; and (2) their modulatory effects on the immune response of the host during infectious and non-infectious diseases.

show abstract

“…Various strategies are currently being employed to combat the severity and spread of coccidiosis in chickens. Some of these control strategies include the use of live vaccines, therapeutic antimicrobial growth promoters (AGPs) and anticoccidial drugs (such as ionophore-based prophylactic drugs) produced from synthetic chemicals and fermentation methods [5,34,57]. The use of these control strategies in previous years has proved effective in controlling the spread of Eimeria infections; however, continuous exposure of animals to live vaccines and AGPs has been discouraged as it poses negative impacts on food animals and indirectly public health concerns to humans [88].…”

Section: Dietary Supplementation For Manipulating the Chicken Gut Micmentioning

confidence: 99%

Understanding the interactions betweenEimeriainfection and gut microbiota, towards the control of chicken coccidiosis: a review

2021

View full text Add to dashboard Cite

The gastrointestinal tract in poultry harbours a diverse microbial community that serves a crucial role in digestion and protection. Disruption of the gut environment due to Eimeria spp. parasite infection causes an imbalance in intestinal homeostasis, driving the increment of pathogens such as Clostridium species. Coccidiosis infection affects the composition and integrity of gut microbiota, resulting in elevated susceptibility to diseases that pose a serious threat to the overall health and productivity of chickens. Anticoccidial drugs have proven effective in curbing coccidiosis but with concerning drawbacks like drug resistance and drug residues in meat. The exploration of natural alternative strategies such as probiotics and phytochemicals is significant in controlling coccidiosis through modification and restoration of gut microbiota, without inducing drug resistance. Understanding the interaction between Eimeria parasites and gut microbiota is crucial for the control and prevention of coccidiosis, and the development of novel alternative treatments.

show abstract

Immunomodulatory and ameliorative effects of Lactobacillus and Saccharomyces based probiotics on pathological effects of eimeriasis in broilers

Cited by 29 publications

References 47 publications

Effects of microbial fermented sesame meal and enzyme supplementation on the intestinal morphology, microbiota, pH, tibia bone and blood parameters of broiler chicks

Effects of microbial fermented sesame meal and enzyme supplementation on the intestinal morphology, microbiota, pH, tibia bone and blood parameters of broiler chicks

Modulatory Effects of Probiotics During Pathogenic Infections With Emphasis on Immune Regulation

Understanding the interactions betweenEimeriainfection and gut microbiota, towards the control of chicken coccidiosis: a review

Contact Info

Product

Resources

About