2021
DOI: 10.3390/ani11010129
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Immunomodulatory Effects of Dietary Phosphorus and Calcium in Two Strains of Laying Hens

Abstract: Insufficient nutrient supply can impair the immune system, which is important for animal health and welfare. Since chicken can partly hydrolyze phytate, which is the primary phosphorus storage in plant seeds, a reduction of mineral phosphorus in the diets could be an option for more sustainable egg production. Laying hens require high concentrations of calcium that might inhibit the function of endogenous enzymes for phytate hydrolyzation. The objective of this study was to characterize the impact of standard … Show more

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Cited by 16 publications
(25 citation statements)
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References 50 publications
(30 reference statements)
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“…The differences point to a generally higher innate and humoral immune response in LB hens and to a more pronounced cellular arm of the immune system in LSL hens. These results are in line with a recent study by Hofmann et al (2021) .…”
Section: Discussionsupporting
confidence: 94%
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“…The differences point to a generally higher innate and humoral immune response in LB hens and to a more pronounced cellular arm of the immune system in LSL hens. These results are in line with a recent study by Hofmann et al (2021) .…”
Section: Discussionsupporting
confidence: 94%
“…One sample of spleen cell suspensions per hen was stored on ice until further processing for immune cell numbers by flow cytometry. In order to obtain mononuclear splenic leukocytes for functional analyses, the remaining spleen cell suspension was further processed by gradient centrifugation to separate mononuclear leukocytes from erythrocytes and thrombocytes as described in Hofmann et al (2021) . The cell suspension was carefully layered onto a gradient (1.077 g/mL Biocoll separation solution, Biochrom, Berlin, Germany).…”
Section: Methodsmentioning
confidence: 99%
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