Immunomodulatory Effects of Nigella Sativa

Abstract

Nigella sativa, commonly referred to as black cumin or black seed, has drawn interest due to possible immunomodulatory properties. Thymoquinone is one of the bioactive chemicals found in N. sativa that has immunomodulatory qualities that can affect the immune system. It can boost immune cell activity, control inflammatory processes, and alter the generation of cytokines, among other immunological responses. Nigella sativa has immunomodulatory properties that may be related to its capacity to control the proportion of T lymphocytes to macrophages, among other immune cells, promoting a more robust and well-balanced immunological response. Thymoquinone has also been linked to decreased inflammation and oxidative stress, which lends credence to its possible immunomodulatory function. In this chapter, the immunomodulatory potential of cumin is discussed.