Immunomodulatory potential of acemannan (polysaccharide from<i>Aloe vera</i>) against radiation induced mortality in Swiss albino mice

Kumar, Sumit; Tiku, Ashu Bhan

doi:10.1080/09540105.2015.1079594

Cited by 57 publications

(52 citation statements)

References 36 publications

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“…Pleurotus nebrodensis polysaccharide is capable of enhancing TNF-α and IL-6 secretion by 62% and 19%, respectively (Cui, Wang, Wang, Li, & Zhang, 2015). Acemannan, a polysaccharide from Aloe vera, can increase TNF-α and IL-1 levels in the irradiated mice (Kumar & Tiku, 2016). Pleurotus tuber-regium (Fr.)…”

Section: Effects Of the Wyps On Cytokines And Enzymes Secretionmentioning

confidence: 99%

Immunomodulatory potentials of the water-soluble yam (Dioscorea opposita Thunb) polysaccharides for the normal and cyclophosphamide-suppressed mice

Hao

Zhao

2016

Food and Agricultural Immunology

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Immunomodulatory potentials of water-soluble yam (Dioscorea opposita Thunb) polysaccharides (WYPs) for the normal and immuno-suppressed mice were described in this study. For the normal mice, the WYPs at 500 mg kg −1 elevated spleen and thymus indices by 22-42%; promoted macrophages' phagocytosis; lymphocytes' proliferation and natural killer (NK) cell activity by 18-53%; enhanced IL-2 and IFN-γ levels in the splenocytes by 42-45%; raised IL-1β, IL-6, TNF-α, iNOS and lysozyme levels in the macrophages by 40-219%; and increased serum IgM, IgA and IgG levels by 44-51%. The WYPs could restore and improve immune status of the cyclophosphamide-treated mice, as they at 500 mg kg −1 elevated spleen and thymus indices by 85-172%; promoted macrophages' phagocytosis, lymphocytes' proliferation and NK cell activity by 24-98%; enhanced IL-2 and IFN-γ levels in the splenocytes by 44-109% or IL-1β, IL-6, TNF-α, iNOS and lysozyme levels in the macrophages by 53-287%; and increased the three immunoglobulins by 24-69%.

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Section: Effects Of the Wyps On Cytokines And Enzymes Secretionmentioning

confidence: 99%

Immunomodulatory potentials of the water-soluble yam (Dioscorea opposita Thunb) polysaccharides for the normal and cyclophosphamide-suppressed mice

Hao

Zhao

2016

Food and Agricultural Immunology

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“…Figure 1 shows the equipment used for VI. This was built based on us the works of [11], [15], [19] and [20], and it is composed of a) an impregnation chamber made of stainless steel with a sample basket and b) a vacuum pump with a vacuum pressure regulator. The yacon slices and Aloe vera solution were analyzed before and after each treatment.…”

Section: Chemicals and Reactantsmentioning

confidence: 99%

“…Aloe vera gel contains mainly polysaccharides, phenolic compounds, organic acids, enzymes, vitamins, and minerals [9]. Moreover, acemannan, a partially acetylated polysaccharide found in Aloe vera gel, is responsible for biological activities [10], [11], [8].…”

Section: Introductionmentioning

confidence: 99%

Optimizing the incorporation of aloe vera in yacon (smallanthus sonchifolius poepp. & endl.) Through vacuum impregnation using response surface

Oblitas

Gutierrez²

2017

IyU

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Objectives: The aim of this research was to optimize the parameters for the vacuum impregnation of aloe vera into dried yacon (Smallanthus sonchifolius Poepp. & Endl.) flakes. Methodology: A surface response methodology was use to evaluate the product optimization. Matrix engineering, using a vacuum impregnation technique, was employed to incorporate components with physiological activity into the pores present in the yacon flakes. An orange pulp yacon was used as the starting material and Aloe Gold Seal-Natural 200X (AGS) was used for the impregnate solution. A solution of 15 g/100 ml Natural aloe 200X Gold Seal-yacon was used to impregnate yacon samples measuring 40 mm in diameter and 5 mm thick. The results show an average impregnation of 0.0721 m3 of solution/ m3 fresh fruit and an effective porosity of 18.97%; the amount of aloe vera incorporated in the food matrix was between 22.5 and 54.6 mg/100g sample. Optimized parameters were identified as 451.777 mbar and 22.0711 minutes. Results: From the results, it is concluded that yacon is an excellent raw material for vacuum impregnation of aloe vera.

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“…Acemannan, a partially acetylated polysaccharide found in the Aloe vera gel, is responsible for its biological activities (Chokboribal et al, 2015;Kumar and Tiku, 2016). Aspargus racemosus of Asparagaceae family has been referred as bitter-sweet, emollient, cooling, nervine tonic, constipating, aphorodisiac, diuretic, rejuvenating, carminative, stomachic, antiseptic and as tonic and also has potent antioxidant, immunostimulant, anti dyspepsia and antitussive effects (Bopana and Saxena, 2007).…”

Section: Introductionmentioning

confidence: 99%

Development of polyherbal granules and its nutritional characterization

Baruah

Arya

Nalwade

et al. 2017

AJDFR

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Two poly herbal granules (AVII and SBWII) were developed utilizing the extracts of five medicinal plants on the basis of organoleptic evaluation, nutritional composition and shelf life. Five medicinal plants viz., Asparagus racemosus, Chlorophytum borivilianum, Tinospora cordifolia, Tribulus terrestris and Withania somnifera enriched with general tonic and health promoting property were selected for the formulations which were based on Aloe vera gel and soyabean whey. The nutrient analysis of the formulated granules exhibited that the carbohydrates were the major constituents in both AVII and SBWII, followed by protein and total ash. Fat contents were 0.96 and 1.18 g/100g in AVII and SBWII, respectively. The energy levels of AVII and SBWII were 378 and 377 Kcal/100g, correspondingly. Higher contents of Ca (70.20 mg/ 100g), Mg (85.27mg/100g) and P (61.55 mg/100g) were observed in SBWII. The trace elements revealed that, Zn and Fe content were 1.84 and 8.63mg/100g in AVII and 1.85 and 7.85mg/100g in SBWII, respectively. The retention and stability of vitamin C, total sugar, reducing sugar and non-reducing sugar for 270 days illustrated the storage life of the product in ambient condition.

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Immunomodulatory potential of acemannan (polysaccharide fromAloe vera) against radiation induced mortality in Swiss albino mice

Cited by 57 publications

References 36 publications

Immunomodulatory potentials of the water-soluble yam (Dioscorea opposita Thunb) polysaccharides for the normal and cyclophosphamide-suppressed mice

Immunomodulatory potentials of the water-soluble yam (Dioscorea opposita Thunb) polysaccharides for the normal and cyclophosphamide-suppressed mice

Optimizing the incorporation of aloe vera in yacon (smallanthus sonchifolius poepp. & endl.) Through vacuum impregnation using response surface

Development of polyherbal granules and its nutritional characterization

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