Immunostimulatory and anti-allergic potential of novel heterotrimeric lectin from seeds of Zizyphus mauritiana Lam

Butle, Ashwin; Talmale, Suhas; Jadhao, Vivek V.; Patil, M. B.; Lambat, Trimurti L.

doi:10.1016/j.ijbiomac.2021.01.027

Cited by 3 publications

(1 citation statement)

References 66 publications

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“…It completely prevented anaphylactic shock and Arthus reaction in the in vivo model. Butle et al, 2021 Stem bark Flavonoid fraction from chloroform extract Immune-stimulatory activity It stimulates phagocytic index, lysosomal degranulation, and proliferation of splenocytes and lymphocytes. Talmale et al, 2014 Leaf Methanol extract Analgesic activity& Antipyretic effect At a dose of 500 mg/kg, the extract significantly reduced the perception of pain brought on by thermal, mechanical, and chemical pain models.…”

Section: Nutraceutical Propertiesmentioning

confidence: 99%

Indian jujube a potential fruit tree to improve the livelihood

Sishu

Das

Selvaraj

2023

Saudi Journal of Biological Sciences

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Section: Nutraceutical Propertiesmentioning

confidence: 99%

Indian jujube a potential fruit tree to improve the livelihood

Sishu

Das

Selvaraj

2023

Saudi Journal of Biological Sciences

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Purification and characterization of a glycoprotein from Sipunculus nudus and its immune-enhancing activity to RAW 264.7 macrophages

Lu,

Dai,

Yang

et al. 2023

Food Research International

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Genomes of autotetraploid wild and cultivated Ziziphus mauritiana reveal polyploid evolution and crop domestication

Guo,

Bi,

Wang

et al. 2024

Plant Physiology

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Indian jujube (Ziziphus mauritiana) holds a prominent position in the global fruit and pharmaceutical markets. Here, we report the assemblies of haplotype-resolved, telomere-to-telomere genomes of autotetraploid wild and cultivated Indian jujube plants using a two-stage assembly strategy. The generation of these genomes permitted in-depth investigations into the divergence and evolutionary history of this important fruit crop. Using a graph-based pan-genome constructed from eight monoploid genomes, we identified structural variation (SV)-FST hotspots and SV hotspots. Gap-free genomes provide a means to obtain a global view of centromere structures. We identified presence-absence variation-related genes in four monoploid genomes (cI, cIII, wI, and wIII) and resequencing populations. We also present the population structure and domestication trajectory of the Indian jujube based on the resequencing of 73 wild and cultivated accessions. Metabolomic and transcriptomic analyses of mature fruits of wild and cultivated accessions unveiled the genetic basis underlying loss of fruit astringency during domestication of Indian jujube. This study reveals mechanisms underlying the divergence, evolution, and domestication of the autotetraploid Indian jujube and provides rich and reliable genetic resources for future research.

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Immunostimulatory and anti-allergic potential of novel heterotrimeric lectin from seeds of Zizyphus mauritiana Lam

Cited by 3 publications

References 66 publications

Indian jujube a potential fruit tree to improve the livelihood

Indian jujube a potential fruit tree to improve the livelihood

Purification and characterization of a glycoprotein from Sipunculus nudus and its immune-enhancing activity to RAW 264.7 macrophages

Genomes of autotetraploid wild and cultivated Ziziphus mauritiana reveal polyploid evolution and crop domestication

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