Immunosuppression in Multiple Sclerosis and Other Neurologic Disorders

Thompson, Kaitlyn Koenig; Tsirka, Stella E.

doi:10.1007/164_2021_545

Cited by 1 publication

(2 citation statements)

References 117 publications

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“…Some clinical conditions, in fact, may be characterized by a limited possibility of accessing in-person health care services due, for example, to immunosuppression and increased susceptibility to infection. Patients with multiple sclerosis (MS) were recruited for testing the feasibility and construct validity of Tele-GEMS [ 2 ].…”

Section: Methodsmentioning

confidence: 99%

“…Tele-neuropsychology may reduce the limitations in assessing individuals who cannot move from their homes to be evaluated for different reasons. Previous studies highlighted the importance of implementing and improving tele-neuropsychological services and care, for groups of individuals that cannot easily reach the health services for risks related to infections, like in the case of immunosuppressive diseases like multiple sclerosis (and other neurological disorders, such as Guillain-Barré syndrome) [ 2 ], showing that remote testing essentially allows a greater access to health care [ 3 , 4 ]. Crucially, although the in-person modality is preferred for detecting clinical and non-clinical signs in a neuropsychological assessment, a significant agreement between tele-neuropsychological and in-person assessment has been shown [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

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Tele-Global Examination of Mental State (Tele-GEMS): an open tool for the remote neuropsychological screening

Montemurro,

Mondini,

Pucci

et al. 2023

Neurol Sci

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Tele-neuropsychology, i.e., the application of remote audio-visual technologies to neuropsychological evaluation or rehabilitation, has become increasingly popular and widespread during and after the COVID-19 pandemic. New tools with updated normative data and appropriate methodological developments are necessary. We present Tele-GEMS, a telephone-based cognitive screening developed on N = 601 Italian participants. It yields a global score tapping on orientation, memory, spatial representation, language, and pragmatic abilities. Its administration lasts about 10 min. Clinical cut-offs are provided, accounting for demographic variables (age, education, and sex) and also for a comprehensive index taking into account cognitively stimulating life experiences that can build up a cognitive reserve. Tele-GEMS shows good internal consistency and a good inter-rater agreement. The test includes the thresholds for estimating a significant change after repeated measurements. Tele-GEMS has a good construct validity as assessed with MoCA and a suitable criterion validity assessed with its in-person version (GEMS). All the materials and the instructions, including scripts and an online Application for the automatic calculation of cut-offs, are accessible on OSF at https://osf.io/t3bma/ under a Creative Commons license. Supplementary Information The online version contains supplementary material available at 10.1007/s10072-023-06862-1.

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Section: Methodsmentioning

confidence: 99%