Immunosuppressive factor from liver and its influence on T cell development

Kazansky, Dmitry; Nastoyashchaya, N. N.; Lomakin, M. S.; Artsimovich, N. G.

doi:10.1016/0165-2478(92)90098-9

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“…Liver proteins with immunosuppressor activity (c~-fetoprotein, etc.) [13], the production of which increases after PHE, may act as immunosuppressors. It should be noted that the production of endotoxin increases considerably within the first 6 h after PHE [9].…”

Section: Resultsmentioning

confidence: 98%

Phlogogenic and hemopoiesis-stimulating activities of liver and lung macrophages upon liver regeneration

et al. 1996

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The phagocytizing and colony-stimulating activities of liver macrophages are increased 36 h after partial hepatectomy. Although the blood count of phagocytizing cells is increased, the rate of the formation of zymosan-induced granulomas in the liver and lungs is decreased. Administration of zymosan after partial hepatectomy inhibits granulomonocytopoiesis in the bone marrow and reduces colony-stimulating activity of Kupffer cells and phagocytizing activity of liver and lung macrophages.

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Section: Resultsmentioning

confidence: 98%