Impact de la pandémie de COVID-19 sur la prise en charge du cancer du sein : retour d’expérience d’un centre de lutte contre le cancer

Tran, Mélanie; Brouard, Nora; Héquet, Delphine; Rouzier, Roman; Donval, Lou

doi:10.1016/j.bulcan.2022.09.004

Cited by 1 publication

(2 citation statements)

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“…In South West France, investigators reported less new BC cases, diagnosed with larger tumors 21 . In Paris region, a comprehensive cancer center reported no impact of the pandemic on clinical presentation or time to treatment, despite a 42% decrease in the number of initial visits for recently diagnosed BC during the first national lockdown (March–May 2020) 22 …”

Section: Introductionmentioning

confidence: 99%

“…21 In Paris region, a comprehensive cancer center reported no impact of the pandemic on clinical presentation or time to treatment, despite a 42% decrease in the number of initial visits for recently diagnosed BC during the first national lockdown (March-May 2020). 22 The aim of this study was to assess the impact of the SARS CoV-2 pandemic on tumor stage at diagnosis, anticancer upfront treatments, and 1-year overall survival (OS) of newly referred BC cases, in the Greater Paris area, before, during, and after the outbreak of the SARS CoV-2 pandemic in early 2020.…”

Section: Introductionmentioning

confidence: 99%

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Impact of the COVID‐19 pandemic on clinical presentation, treatments, and outcomes of new breast cancer patients: A retrospective multicenter cohort study

Guével,

Priou,

Lamé

et al. 2023

Cancer Medicine

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BackgroundThe SARS CoV‐2 pandemic disrupted healthcare systems. We compared the cancer stage for new breast cancers (BCs) before and during the pandemic.MethodsWe performed a retrospective multicenter cohort study on the data warehouse of Greater Paris University Hospitals (AP‐HP). We identified all female patients newly referred with a BC in 2019 and 2020. We assessed the timeline of their care trajectories, initial tumor stage, and treatment received: BC resection, exclusive systemic therapy, exclusive radiation therapy, or exclusive best supportive care (BSC). We calculated patients' 1‐year overall survival (OS) and compared indicators in 2019 and 2020.ResultsIn 2019 and 2020, 2055 and 1988, new BC patients underwent cancer treatment, and during the two lockdowns, the BC diagnoses varied by −18% and by +23% compared to 2019. De novo metastatic tumors (15% and 15%, p = 0.95), pTNM and ypTNM distributions of 1332 cases with upfront resection and of 296 cases with neoadjuvant therapy did not differ (p = 0.37, p = 0.3). The median times from first multidisciplinary meeting and from diagnosis to treatment of 19 days (interquartile 11–39 days) and 35 days (interquartile 22–65 days) did not differ. Access to plastic surgery (15% and 17%, p = 0.08) and to treatment categories did not vary: tumor resection (73% and 72%), exclusive systemic therapy (13% and 14%), exclusive radiation therapy (9% and 9%), exclusive BSC (5% and 5%) (p = 0.8). Among resected patients, the neoadjuvant therapy rate was lower in 2019 (16%) versus 2020 (20%) (p = 0.02). One‐year OS rates were 99.3% versus 98.9% (HR = 0.96; 95% CI, 0.77–1.2), 72.6% versus 76.6% (HR = 1.28; 95% CI, 0.95–1.72), 96.6% versus 97.8% (HR = 1.09; 95% CI, 0.61–1.94), and 15.5% versus 15.1% (HR = 0.99; 95% CI, 0.72–1.37), in the treatment groups.ConclusionsDespite a decrease in the number of new BCs, there was no tumor stage shift, and OS did not vary.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%