Abstract:In the context of climate change in West Africa characterized by a reduction of precipitation, this study was conducted to evaluate the impact of climate change on water resources from now to the end of the 21st century in the transboundary watershed of the Sassandra River shared by Guinea and (1961)(1962)(1963)(1964)(1965)(1966)(1967)(1968)(1969)(1970)(1971)(1972)(1973)(1974)(1975)(1976)(1977)(1978)(1979)(1980). For RCP 4.5, the observed values go from −1.2% in 2030 to −2.3% in 2070 and rise to −2.1% in 2090. Concerning RCP 8.5, we saw a variation from −4.2 to −7.9% in Horizons 2030 and 2090, respectively. With the general decrease in rainfall in West Africa, it is appropriate to assess the impact on water resources of the largest rivers (Niger, Gambia, and Senegal) that irrigate the Sahelo-Saharian zone.