Impact of 2011 French guidelines on antibiotic prescription for acute otitis media in infants

Lévy, Corinne; Pereira, Marcy Lancia; Guedj, Romain; Abt-Nord, C.; Gelbert, Nathalie; Cohen, Robert; Alberti, Corinne; Gajdos, Vincent; Angoulvant, François

doi:10.1016/j.medmal.2014.01.005

Cited by 22 publications

(23 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A French study 42 found appropriate antibiotic choice 66% of the time; the comparable indicator (OTIT12) was 62% in the current study. In general, however, studies did not measure or report adherence to guidelines in the same way as CTK.…”

Section: Comparison With Other Studiessupporting

confidence: 48%

Assessing the appropriateness of the management of otitis media in Australia: A population‐based sample survey

Clay‐Williams

Stephens

Williams

et al. 2019

J Paediatrics Child Health

View full text Add to dashboard Cite

Aim Acute otitis media (AOM) is the most common infectious disease for which antibiotics are prescribed; its management is costly and has the potential to increase the antimicrobial resistance of this infection. This study measured the levels of adherence to the clinical practice guidelines (CPGs) of AOM and otitis media with effusion (OME) management in Australian children. Methods We searched for national and international CPGs relating to AOM and OME in children and created 37 indicators for assessment. We reviewed medical records for adherence to these indicators in 120 locations, across one inpatient and three ambulatory health‐care settings. Our review sample was obtained from three Australian states that contain 60% of the nation's children. Results We reviewed the records of 1063 children with one or more assessments of CPG adherence for otitis media. Of 22 indicators with sufficient data, estimated adherence ranged from 7.4 to 99.1%. Overuse of treatment, particularly overprescribing of antibiotics, was more common than underuse. A frequent lack of adherence with recommended care was observed for children aged between 1 and 2 years with AOM. Adherence varied by health‐care setting, with emergency departments and inpatient settings more adherent to CPGs than general practices. Conclusions Our assessment of a number of indicators in the common settings in which otitis media is treated found that guideline adherence varied widely between individual indicators. Internationally agreed standards for diagnosis and treatment, coupled with clinician education on the existence and content of CPGs and clinical decision support, are needed to improve the management of children presenting with AOM and OME.

show abstract

Section: Comparison With Other Studiessupporting

confidence: 48%

Assessing the appropriateness of the management of otitis media in Australia: A population‐based sample survey

Clay‐Williams

Stephens

Williams

et al. 2019

J Paediatrics Child Health

View full text Add to dashboard Cite

show abstract

“…The emergency department (ED) needs to be a target for interventions in the field of paediatric antibiotic stewardship since a large proportion of acute care outpatient visits occur in this setting 4 5. In particular, upper respiratory tract infections (URTIs) are the most common reason for antibiotic prescriptions to children in both outpatient and ED settings 6–8. Antibiotic prescribing patterns to children attending ED do not appear to have been widely evaluated, and studies have mainly focused on a few countries and/or were on respiratory or urinary tract infections 6–21…”

Section: Introductionmentioning

confidence: 99%

“…Giving the paucity of information on the antibiotic prescriptions in ED, the aim of this study was to investigate the pattern of antibiotic prescriptions in EDs in a large Italian region by analysing administrative healthcare databases, and to compare the patterns of prescriptions filled by primary care physicians and those prescribed in ED. We also evaluated the appropriateness of antibiotic prescription, in terms of choice of drugs recommended by the guidelines, in children seen in ED for URTIs, which represent one of the most common reasons for ED access, and are frequently associated with antibiotic treatment both in primary care and ED setting 2 6–8 22…”

Section: Introductionmentioning

confidence: 99%

Antibiotic prescription in the outpatient paediatric population attending emergency departments in Lombardy, Italy: a retrospective database review

Messina

Clavenna

Cartabia

et al. 2019

bmjpo

View full text Add to dashboard Cite

ObjectivesThis study aimed to assess the appropriateness of antibiotic prescription in children seen in emergency departments (EDs) and to compare prescription profiles in ED and primary care.DesignThis is a retrospective analysis of healthcare administrative databases.SettingThe study analysed data collected in emergency departments (EDs) and primary care practices (PCPs) in Lombardy, Italy.ParticipantsChildren and adolescents between 1 and 13 years old with an ED access and/or an antibiotic prescription in the first semester of 2012 participated in the study. Only those with an index event (ie, without ED access, hospital admissions or antibiotic prescriptions in the previous 60 days) were included.Main outcome measuresThe main outcomes are percentage of subjects receiving amoxicillin (first-choice antibiotic) and percentages receiving macrolides/cephalosporins (second-choice therapies).ResultsDuring the observation period, 133 275 children had one ED access, and 26 087 (19.6%) received an antibiotic prescription. In all, 56.1% of children seen for upper respiratory tract infections (URTIs) received an antibiotic, with a prevalence of 67.8% for otitis media and 56.4% for pharyngotonsillitis; 22.3% of children were given amoxicillin after a visit for URTIs, with no differences among infections, and 19.6% received macrolides and cephalosporins. Few differences were found when comparing the index antibiotic prescriptions in ED and PCP settings. A higher prescription of second-choice antibiotics was observed among children cared for by PCPs compared with children attending EDs (31.3% vs 23.4%, χ2 M-H=720, p<0.001). The place of residence was the main determinant of the qualitative profile of prescriptions.ConclusionsMore must be done to improve rational use of antibiotics in the ED and PCP setting, and educational interventions including physicians in both setting are strongly needed.

show abstract

“…Data were aggregated for suspected and/or interacting drugs at the level of medicinal product name according to International Nonproprietary Names and for events at the level of MedDRA Preferred Term (PT) or related Standardized MedDRA Queries (SMQs). Standardized MedDRA Queries are validated standard sets of MedDRA terms which were used to avoid missing cases …”

Section: Methodsmentioning

confidence: 99%

“…In the field of public health surveillance, CPA was applied for the first time by Kass-Hout et al 5 MedDRA Queries are validated standard sets of MedDRA terms which were used to avoid missing cases. 7 We extracted from BNPV and EV number of reports, dynamic PRR and their confidence intervals for each couple drug-ADR. A signal of disproportionate reporting (SDR) is defined by 2 thresholds: lower bound of PRR (PRR-) ≥ 1 with at least 5 cases.…”

Section: Introductionmentioning

confidence: 99%

Benefits of combining change‐point analysis with disproportionality analysis in pharmacovigilance signal detection

Trinh

Sole

Benkebil

2018

Pharmacoepidemiology and Drug

View full text Add to dashboard Cite

show abstract

Impact of 2011 French guidelines on antibiotic prescription for acute otitis media in infants

Cited by 22 publications

References 12 publications

Assessing the appropriateness of the management of otitis media in Australia: A population‐based sample survey

Assessing the appropriateness of the management of otitis media in Australia: A population‐based sample survey

Antibiotic prescription in the outpatient paediatric population attending emergency departments in Lombardy, Italy: a retrospective database review

Benefits of combining change‐point analysis with disproportionality analysis in pharmacovigilance signal detection

Contact Info

Product

Resources

About