Impact of a Modified Needle Tip Geometry on Penetration Force as Well as Acceptability, Preference, and Perceived Pain in Subjects with Diabetes

Hirsch, Laurence; Gibney, Michael A.; Bérubé, Julie; Manocchio, John

doi:10.1177/193229681200600216

Cited by 78 publications

(74 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Use of either prefilled disposable or reusable pens can overcome some of the patient challenges to initiation of insulin therapy and may improve patient adherence and, possibly, patient outcomes 76. A study comparing a modified five-bevel needle pen tip (available globally since 2005) with that of a marketed three-bevel needle pen tip showed that pen geometry affects the penetrating force and, consequently, patient preferences 73. Moreover, compared to vials and syringes, insulin pens are preferred because they are easy to use, convenient, and deliver a precise and controlled amount of insulin 115.…”

Section: Resultsmentioning

confidence: 99%

Identifying and meeting the challenges of insulin therapy in type 2 diabetes

Sorli¹,

Heile²

2014

JMDH

View full text Add to dashboard Cite

Type 2 diabetes mellitus (T2DM) is a chronic illness that requires clinical recognition and treatment of the dual pathophysiologic entities of altered glycemic control and insulin resistance to reduce the risk of long-term micro- and macrovascular complications. Although insulin is one of the most effective and widely used therapeutic options in the management of diabetes, it is used by less than one-half of patients for whom it is recommended. Clinician-, patient-, and health care system-related challenges present numerous obstacles to insulin use in T2DM. Clinicians must remain informed about new insulin products, emerging technologies, and treatment options that have the potential to improve adherence to insulin therapy while optimizing glycemic control and mitigating the risks of therapy. Patient-related challenges may be overcome by actively listening to the patient’s fears and concerns regarding insulin therapy and by educating patients about the importance, rationale, and evolving role of insulin in individualized self-treatment regimens. Enlisting the services of Certified Diabetes Educators and office personnel can help in addressing patient-related challenges. Self-management of diabetes requires improved patient awareness regarding the importance of lifestyle modifications, self-monitoring, and/or continuous glucose monitoring, improved methods of insulin delivery (eg, insulin pens), and the enhanced convenience and safety provided by insulin analogs. Health care system-related challenges may be improved through control of the rising cost of insulin therapy while making it available to patients. To increase the success rate of treatment of T2DM, the 2012 position statement from the American Diabetes Association and the European Association for the Study of Diabetes focused on individualized patient care and provided clinicians with general treatment goals, implementation strategies, and tools to evaluate the quality of care.

show abstract

Section: Resultsmentioning

confidence: 99%

Identifying and meeting the challenges of insulin therapy in type 2 diabetes

Sorli¹,

Heile²

2014

JMDH

View full text Add to dashboard Cite

show abstract

“…53 Patients also found the five-bevel less painful, but the difference did not reach statistical significance. Very recently, Hirsch et al 54 studied needles from several manufacturers in several gauges, ranging from 30-gauge to 32-gauge, to compare a new five-bevel needle tip to the standard three-bevel design. Penetration force during computer-controlled insertions using a human skin substitute was 23.7% less using a five-bevel tip versus matched needles with a three-bevel tip.…”

Section: Aronsonmentioning

confidence: 99%

The Role of Comfort and Discomfort in Insulin Therapy

Aronson

2012

Diabetes Technology & Therapeutics

View full text Add to dashboard Cite

Despite the recognized importance of optimal insulin therapy, patient adherence to insulin therapy is an ongoing clinical care challenge. Insulin omission continues to be frequent and underestimated and has been correlated with poorer glycemic control and increased rates of diabetes-related complications. Insulin users consistently indentify multiple factors that contribute to insulin injection-related anxiety and to non-adherence. Injection-related discomfort continues to bear a significant contribution. Over the last decade, with advances in needle manufacturing technology, shorter and narrower needles have been associated with progressively improving patient self-rating of injection discomfort. Consequently, patient surveys of insulin users show discomfort to rank in the bottom third of significant contributors by prevalence. However, healthcare providers (HCP) and family member care providers continue to demonstrate a high level of anticipated and perceived pain for the patient. HCP anxiety and pain anticipation are each associated with patient anxiety and may therefore play a significant contributing role in patient non-adherence.

show abstract

“…An in vitro study comparing trifacet and pentafacet hypodermic needles demonstrated that the bevel geometry has a direct relation with the strength necessary for the penetration of needles into an artificial substitute of human skin (19) . Thus, the theory that seems to thrive is that of needles change between preparation and subcutaneous drug administration, as a way of guaranteeing the morphology of the bevels, can have a positive influence on the perception of discomfort in patients who use drugs through this route.…”

Section: Discussionmentioning

confidence: 99%

Avaliação ultraestrutural de agulhas e seu papel no conforto durante a administração subcutânea de medicamentos

Pereira

Oliveira

Ferreira

et al. 2018

Rev. esc. enferm. USP

View full text Add to dashboard Cite

RESUMO Objetivo Avaliar a morfologia de biséis de agulhas hipodérmicas após a aspiração de drogas e a percepção de conforto ocasionado pela troca ou não de agulhas entre preparo e administração de medicamentos pela via subcutânea. Método Pesquisa experimental realizada em dois momentos. Inicialmente, agulhas hipodérmicas foram analisadas por microscopia eletrônica de varredura e, em seguida, um ensaio piloto foi conduzido com os participantes, que indicaram o nível de conforto percebido no momento da penetração dos biséis das agulhas durante a administração pela via subcutânea. Resultados Participaram do estudo 41 pacientes adultos internados. Apesar de as agulhas terem apresentado de discreta a importante alteração morfológica, quando avaliadas por ultramicroscopia, os participantes deste estudo não foram capazes de relatar alterações sensoriais significativas durante a penetração destas nas duas técnicas adotadas. Conclusões A padronização de seringas com agulhas fixas ou o uso de uma única agulha tanto para o preparo quanto para a administração de medicamentos pela via subcutânea devem ser considerados como estratégias para redução da produção de resíduos perfurocortantes, diminuição do custo por procedimento e limitação do risco de contaminação de dispositivos considerados críticos.

show abstract

Impact of a Modified Needle Tip Geometry on Penetration Force as Well as Acceptability, Preference, and Perceived Pain in Subjects with Diabetes

Abstract: Background:

Cited by 78 publications

References 24 publications

Identifying and meeting the challenges of insulin therapy in type 2 diabetes

Identifying and meeting the challenges of insulin therapy in type 2 diabetes

The Role of Comfort and Discomfort in Insulin Therapy

Avaliação ultraestrutural de agulhas e seu papel no conforto durante a administração subcutânea de medicamentos

Contact Info

Product

Resources

About