Impact of a New Portable Air Purification Technology Device in the Pediatric Hospital Setting – A Pre-post Assessment Study

Rao, Nikhil G.; Kumar, Amit; Colon, Chelsea; Goswami, D. Yogi

doi:10.7759/cureus.7440

Cited by 6 publications

(7 citation statements)

References 17 publications

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“…A total of 562 patients diagnosed with infectious or noninfectious respiratory distress were included in this study in pre- and post-cohorts. Results showed that the rate of using invasive patient ventilation (i.e., intubation) was reduced 30%, and the average hospitalization time declined from 0.7 days to 0.4 days upon placing the portable air purifier in the rooms, though these differences did not achieve statistical significance. Further, clinical details were not provided to allow a better understanding of potential differences in specific clinical outcomes such as healthcare associated pneumonias, so it is difficult to understand these changes.…”

Section: Filtration In Healthcare Facilitiesmentioning

confidence: 96%

COVID-19 Outbreak and Hospital Air Quality: A Systematic Review of Evidence on Air Filtration and Recirculation

Mousavi

Kananizadeh²,

Martinello

et al. 2020

Environ. Sci. Technol.

116

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The outbreak of SARS-CoV-2 has made us all think critically about hospital indoor air quality and the approaches to remove, dilute, and disinfect pathogenic organisms from the hospital environment. While specific aspects of the coronavirus infectivity, spread, and routes of transmission are still under rigorous investigation, it seems that a recollection of knowledge from the literature can provide useful lessons to cope with this new situation. As a result, a systematic literature review was conducted on the safety of air filtration and air recirculation in healthcare premises. This review targeted a wide range of evidence from codes and regulations, to peer-reviewed publications, and best practice standards. The literature search resulted in 394 publications, of which 109 documents were included in the final review. Overall, even though solid evidence to support current practice is very scarce, proper filtration remains one important approach to maintain the cleanliness of indoor air in hospitals. Given the rather large physical footprint of the filtration system, a range of short-term and long-term solutions from the literature are collected. Nonetheless, there is a need for a rigorous and feasible line of research in the area of air filtration and recirculation in healthcare facilities. Such efforts can enhance the performance of healthcare facilities under normal conditions or during a pandemic. Past innovations can be adopted for the new outbreak at low-to-minimal cost.

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Section: Filtration In Healthcare Facilitiesmentioning

confidence: 96%

COVID-19 Outbreak and Hospital Air Quality: A Systematic Review of Evidence on Air Filtration and Recirculation

Mousavi

Kananizadeh²,

Martinello

et al. 2020

Environ. Sci. Technol.

116

View full text Add to dashboard Cite

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“…Out of the 24 studies that fulfilled our inclusion criteria [ [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] ], 17 studies were conducted and published between 2020 and 2022 during the COVID-19 outbreaks. However, only one study described the detection of SARS-CoV-2 RNA in air samples collected in addition to other airborne microbes (a range of other bacterial, viral, and fungal pathogens) [ 23 ].…”

Section: Resultsmentioning

confidence: 99%

“…They need approximately 45,000 patients to attain a power of 80% 60 months Results are not published yet. Arikan et al, 2021 [ 19 ] Decreased rate of hospital-acquired infections in ICUs in a hospital Non-randomised prospective study 8 months Significant positive correlation with the decreased rate of hospital-acquired infections Rao et al, 2020 [ 31 ] Improvement of health outcomes for patients admitted with respiratory distress in the paediatric hospital setting Non-randomised prospective study of 562 patients 3 months Non-significant association with the decreased overall length of stay in the hospital and ICU, intubation, nebuliser, and non-invasive ventilation use . However, the authors reported that these reductions were clinically meaningful with a significant impact on the healthcare system.…”

Section: Resultsmentioning

confidence: 99%

“…In summary, 20 of 24 studies demonstrated significant potential to prevent and mitigate the impact of bioaerosols in healthcare environments, regardless of the scenario and methodology used. In the remaining 4 studies (3 in-situ studies and one prospective study) the reduction of aerosols was non-significant [ 28 , 31 , 32 , 38 ]. However, in the prospective study the authors commented that a as dental clinics, where economic issues or lack of guidelines may limit the installation of an appropriate ventilation system.…”

Section: Discussionmentioning

confidence: 99%

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The implementation of portable air-cleaning technologies in healthcare settings – a scoping review

Alvarenga

Dias²,

Lima³

et al. 2023

Journal of Hospital Infection

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“… 8 , 9 In terms of expressing measured efficacy, some authors have used disease incidence or frequency of disease symptoms in a setting as a measurement method. 10 , 11 …”

Section: Introductionmentioning

confidence: 99%

Room-Based Assessment of Mobile Air Cleaning Devices Using a Bioaerosol Challenge

et al. 2023

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Introduction: The widespread transmission of the SARS-CoV-2 virus has increased scientific and societal interest in air cleaning technologies, and their potential to mitigate the airborne spread of microorganisms. Here we evaluate room scale use of five mobile air cleaning devices. Methods: A selection of air cleaners, containing high efficiency filtration, was tested using an airborne bacteriophage challenge. Assessments of bioaerosol removal efficacy were undertaken using a decay measurement approach over 3 h, with air cleaner performance compared with bioaerosol decay rate without an air cleaner in the sealed test room. Evidence of chemical by-product emission was also checked, as were total particle counts. Results: Bioaerosol reduction, exceeding natural decay, was observed for all air cleaners. Reductions ranged between devices from <2-log per m 3 room air for the least effective, to a >5-log reduction for the most efficacious systems. One system generated detectable ozone within the sealed test room, but ozone was undetectable when the system was run in a normally ventilated room. Total particulate air removal trends aligned with measured airborne bacteriophage decline. Discussion: Air cleaner performance differed, and this could relate to individual air cleaner flow specifications as well as test room conditions, such as air mixing during testing. However, measurable reductions in bioaerosols, beyond natural airborne decay rate, were observed. Conclusion: Under the described test conditions, air cleaners containing high efficiency filtration significantly reduced bioaerosol levels. The best performing air cleaners could be investigated further with improved assay sensitivity, to enable measurement of lower residual levels of bioaerosols.

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Impact of a New Portable Air Purification Technology Device in the Pediatric Hospital Setting – A Pre-post Assessment Study

Cited by 6 publications

References 17 publications

COVID-19 Outbreak and Hospital Air Quality: A Systematic Review of Evidence on Air Filtration and Recirculation

COVID-19 Outbreak and Hospital Air Quality: A Systematic Review of Evidence on Air Filtration and Recirculation

The implementation of portable air-cleaning technologies in healthcare settings – a scoping review

Room-Based Assessment of Mobile Air Cleaning Devices Using a Bioaerosol Challenge

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