Impact of a proprietary concentrate of Sambucus nigra L. on urinary pH

Abstract

A proprietary concentrate from Sambucus nigra L.--in its diluted preparation as part of a hypocaloric diet available in Switzerland--had no impact on urinary pH, urinary hydrogen ion concentrations or 24 h excretion and thus did not influence the solubility of stone-inducing ions.

A systematic review on the sambuci fructus effect and efficacy profiles

“…Adverse events did not occur. Consumption of a proprietary juice concentrate (Sambu-Holunderkur R , 200 mL per day based on 120 g fresh berries supplemented with flower juice and extract based on 3.9 g dried flowers, diluted 1:5, yielding 400 kcal/day divided into up to six portions) had no impact on urinary hydrogen concentrations or excretions (Walz and Chrubasik, 2008). It is worth noting, however, that consumption of unripe berries or self-prepared juice that has been insufficiently heated or contains leaf or stem may cause toxic effects (Anonymous, 1994).…”

Bioactive properties of Sambucus nigra L. as a functional ingredient for food and pharmaceutical industry

“…Furthermore, supplementation with 1.25% of elderberry extract of hyperlipidemic mice was conducted in order to determination the effect on atherosclerosis and HDL dysfunctions. It Prevention of the initiation and promotion of cancerogenesis stages: strong induction of quinone reductase and inhibition of cyclooxygenase-2 Thole et al (2006) 200 ml divided into up 6 portions 7 days An average weight reduction was 2.6 kg; no effect on pH, hydrogen ion concentration and 24 h hydrogen excretion in urine; no effect on the solubility of stone-inducing ions Walz and Chrubasik (2008) (continued on next page)…”

“…Moreover, physical and mental well-being as well as the quality of life of the patients significantly improved . A diluted concentrate from elder berries and flowers, used among others in hypocaloric diet in Switzerland, resulted in average weight loss of 2.6 kg in 11 volunteers during 7 days of diet (Walz & Chrubasik, 2008). Mahmoudi et al (2014) evaluated the antidepressant activity of elderberry extracts by exposing mice to the forced swimming test (FST) and the tail suspension test (TST).…”

“…Research on the impact of some proprietary elder concentrate on the urinary electrolyte balance showed that 200 ml of concentrate made from fresh berries, flower juice and dried flower extract, did not influence pH, hydrogen ion concentration and 24 h hydrogen excretion in urine collected from 11 participants. Elderberry concentrate also had no impact on the solubility of stone-inducing ions, which suggests that it can be used in patients with idiopathic nephrolithiasis without any risk of harm (Walz & Chrubasik, 2008). Elderberry as a dietary supplement in the form of capsules containing flower extract had no apparent inhibitory effect on uridine diphospho-glucuronosyltransferase (UGTs).…”

Herbal Medicines in the Management of Urolithiasis: Alternative or Complementary?

“…There are a growing number of studies purporting diuretic effects with traditional medicines. Of these, the most promising are Solidago virgaurea L. [74], Sambucus nigra L. [75] and Hibiscus sabdariffa L. [76,77]. Prasongwatana et al [77] also report an increased uric acid excretion and clearance after consumption of H. sabdariffa tea in study subjects with or without a history of renal stones.…”