“…There was selective reporting in 33 trials, 52-57, 59, 62-64, 66, 68-72, 75-77, 79, 81-83, 86, 87, 89-93, 96, 98, 99 insufficient details on attrition in 8 trials, 53,59,61,70,72,75,91,98 inadequate explanation of allocation concealment in 24 trials, 53-57, 63-65, 69, 71, 72, 75, 79, 82, 86, 87, 89, 91-93, 95, 96, 98, 99 lack of assessor blinding in 22 trials, 53-56, 62, 66, 67, 69, 71, 72, 75, 76, 79, 81, 83, 86, 92, 93, 95, 97-99 and inadequate randomization in 9 trials. 69,71,75,76,86,92,93,98,99 Only 10 trials (21%) had low overall risk of bias. 51,58,60,73,78,80,84,85,88,94…”